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Causal Relationship Between Kidney Function and Cancer Risk: A Mendelian Randomization Study
American Journal of Kidney Diseases ( IF 9.4 ) Pub Date : 2024-07-30 , DOI: 10.1053/j.ajkd.2024.05.016
Ellen Dobrijevic 1 , Anita van Zwieten 1 , Andrew J Grant 2 , Clement T Loy 3 , Jonathan C Craig 4 , Armando Teixeira-Pinto 1 , Germaine Wong 5
Affiliation  

Patients treated with kidney replacement therapy experience a 1.5- to 2-fold increased risk of cancer and cancer mortality compared with the general population. Whether this excess risk extends to people with earlier stage chronic kidney disease and whether reduced kidney function is causally related to cancer is unclear.

中文翻译:


肾功能与癌症风险之间的因果关系:一项孟德尔随机化研究



与普通人群相比,接受肾脏替代疗法治疗的患者患癌症的风险和癌症死亡率增加 1.5 至 2 倍。这种过度风险是否延伸到早期慢性肾病患者,以及肾功能下降是否与癌症有因果关系尚不清楚。
更新日期:2024-07-30
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