Chronic inflammation poses challenges to effective cancer treatment. Although anti‐inflammatory therapies have shown short‐term benefits, their long‐term implications may be unfavorable because they fail to initiate the necessary inflammatory responses. Recent research underscores the promise of specialized pro‐resolving mediators, which play a role in modulating the cancer microenvironment by promoting the resolution of initiated inflammatory processes and restoring tissue hemostasis. This review addresses current insights into how inflammation contributes to cancer pathogenesis and explores recent strategies to resolve inflammation associated with cancer.

中文翻译：

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慢性炎症和癌症的消退


慢性炎症对有效的癌症治疗构成挑战。尽管抗炎疗法显示出短期益处，但其长期影响可能是不利的，因为它们无法引发必要的炎症反应。最近的研究强调了专门的促消退介质的前景，它通过促进引发的炎症过程的消退和恢复组织止血，在调节癌症微环境中发挥作用。本综述讨论了当前对炎症如何促进癌症发病机制的见解，并探讨了解决与癌症相关的炎症的最新策略。