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Long-term Trajectories of Low Back Pain in Older Men: A Prospective Cohort Study With 10-Year Analysis of the Osteoporotic Fractures in Men Study
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences ( IF 4.3 ) Pub Date : 2024-07-12 , DOI: 10.1093/gerona/glae175
David T McNaughton 1, 2 , Eric J Roseen 3, 4 , Sheena Patel 5 , Aron Downie 6 , Cecilie K Øverås 7 , Casper Nim 8, 9 , Steen Harsted 8, 9 , Hazel Jenkins 6 , James J Young 9, 10 , Jan Hartvigsen 9, 11 , Jessica J Wong 12 , Katie L Stone 5, 13 , Kristine E Ensrud 14 , Soomi Lee 15 , Peggy M Cawthon 5, 13 , Howard A Fink 14, 16
Affiliation  

Although low back pain (LBP) may persist or recur over time, few studies have evaluated the individual course of LBP over a long-term period, particularly among older adults. Based on data from the longitudinal Osteoporotic Fractures in Men (MrOS) Study, we aimed to identify and describe different LBP trajectories in older men and characterize members in each trajectory group. A total of 5 976 community-dwelling men (mean age = 74.2) enrolled at 6 U.S. sites were analyzed. Participants self-reported LBP (yes/no) every 4 months for a maximum of 10 years. Latent class growth modeling was performed to identify unique LBP trajectory groups that explained variation in the LBP data. The association of baseline characteristics with trajectory group membership was assessed using univariable and multivariable multinominal logistic regression. A 5-class solution was chosen; no/rare LBP (n = 2 442/40.9%), low frequency-stable LBP (n = 1 040/17.4%), low frequency-increasing LBP (n = 719/12%), moderate frequency-decreasing LBP (n = 745/12.5%), and high frequency-stable LBP (n = 1 030/17.2%). History of falls (OR = 1.52), history of LBP (OR = 6.37), higher physical impairment (OR = 1.51–2.85), and worse psychological function (OR = 1.41–1.62) at baseline were all associated with worse LBP trajectory groups in this sample of older men. These findings present an opportunity for targeted interventions and/or management to older men with worse or increasing LBP trajectories and associated modifiable risk factors to reduce the impact of LBP and improve quality of life.

中文翻译:


老年男性腰痛的长期轨迹:一项对男性骨质疏松性骨折研究进行 10 年分析的前瞻性队列研究



尽管腰痛 (LBP) 可能会随着时间的推移而持续或复发,但很少有研究评估 LBP 的长期个体病程,尤其是在老年人中。根据男性纵向骨质疏松性骨折 (MrOS) 研究的数据,我们旨在识别和描述老年男性的不同 LBP 轨迹,并描述每个轨迹组中的成员。共分析了在美国 6 个地点招募的 5 976 名社区居住男性 (平均年龄 = 74.2)。参与者每 4 个月自我报告 LBP(是/否),最长 10 年。执行潜在类别生长模型以确定解释 LBP 数据变化的独特 LBP 轨迹组。使用单变量和多变量多名词 logistic 回归评估基线特征与轨迹组成员身份的关联。选择了一个 5 类解决方案;无/罕见 LBP (n = 2 442/40.9%)、低频稳定 LBP (n = 1 040/17.4%)、低频增加 LBP (n = 719/12%)、中度频率降低 LBP (n = 745/12.5%) 和高频稳定 LBP (n = 1 030/17.2%)。跌倒史 (OR = 1.52)、LBP 病史 (OR = 6.37)、基线时较高的身体损伤 (OR = 1.51-2.85) 和较差的心理功能 (OR = 1.41-1.62) 都与更差的 LBP 轨迹组相关在这个老年男性样本中。这些发现为对 LBP 轨迹恶化或增加的老年男性以及相关的可改变风险因素的老年男性提供了有针对性的干预和/或管理的机会,以减少 LBP 的影响并改善生活质量。
更新日期:2024-07-12
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