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Distinct regional vulnerability to Aβ and iron accumulation in post mortem AD brains
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2024-08-23 , DOI: 10.1002/alz.14188 Junye Yao 1, 2 , Zhenghao Li 3 , Zihan Zhou 1, 4 , Aimin Bao 5 , Zheng Wang 6, 7 , Hongjiang Wei 3 , Hongjian He 1, 8, 9
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2024-08-23 , DOI: 10.1002/alz.14188 Junye Yao 1, 2 , Zhenghao Li 3 , Zihan Zhou 1, 4 , Aimin Bao 5 , Zheng Wang 6, 7 , Hongjiang Wei 3 , Hongjian He 1, 8, 9
Affiliation
The paramagnetic iron, diamagnetic amyloid beta (Aβ) plaques and their interaction are crucial in Alzheimer's disease (AD) pathogenesis, complicating non-invasive magnetic resonance imaging for prodromal AD detection.
中文翻译:
死后 AD 大脑对 Aβ 和铁积累的明显区域易感性
顺磁性铁、抗磁性淀粉样蛋白 β (Aβ) 斑块及其相互作用在阿尔茨海默病 (AD) 发病机制中至关重要,使前驱 AD 检测的无创磁共振成像变得复杂。
更新日期:2024-08-23
中文翻译:
死后 AD 大脑对 Aβ 和铁积累的明显区域易感性
顺磁性铁、抗磁性淀粉样蛋白 β (Aβ) 斑块及其相互作用在阿尔茨海默病 (AD) 发病机制中至关重要,使前驱 AD 检测的无创磁共振成像变得复杂。