Polymer adhesives play an important role in many medical, consumer, and industrial products. Polymers of α-lipoic acid (αLA) have the potential to fulfill the need for versatile and environmentally friendly adhesives, but their performance is plagued by spontaneous depolymerization. We report a family of stabilized αLA polymer adhesives that can be tailored for a variety of medical or nonmedical uses and sustainably sourced and recycled in a closed-loop manner. Minor changes in monomer composition afforded a pressure-sensitive adhesive that functions well in dry and wet conditions, as well as a structural adhesive with strength equivalent to that of conventional epoxies. αLA surgical superglue successfully sealed murine amniotic sac ruptures, increasing fetal survival from 0 to 100%.

中文翻译：

---

可回收的聚（α-硫辛酸）外科、消费和工业粘合剂


聚合物粘合剂在许多医疗、消费品和工业产品中发挥着重要作用。 α-硫辛酸（αLA）聚合物有潜力满足多功能和环保粘合剂的需求，但其性能受到自发解聚的影响。我们报告了一系列稳定的 αLA 聚合物粘合剂，可针对各种医疗或非医疗用途进行定制，并以闭环方式可持续采购和回收。单体组成的微小变化提供了在干燥和潮湿条件下均能良好发挥作用的压敏粘合剂，以及强度与传统环氧树脂相当的结构粘合剂。 αLA 手术强力胶成功密封了小鼠羊膜囊破裂，将胎儿存活率从 0% 提高到 100%。