Movement behaviors within the 24‐h day, including physical activity (PA), sedentary time, and sleep, are associated with cardiometabolic health. We aimed to determine the association between 24‐h movement composition and cardiometabolic health while accounting for sleep efficiency. Altogether, 1134 participants from the Northern Finland Birth Cohort 1986 study, free from prior cardiovascular disease, provided at least 4 days of 24‐h activity and sleep efficiency measured with a wearable ring. Participants' body composition was assessed with bioimpedance, blood pressure, and waist circumference were measured, and lipids and glucose were analyzed from a fasting blood sample. Linear regression models for cardiometabolic outcomes were created with 24‐h movement composition and covariates, including sleep efficiency and behavioral and socioeconomic factors. Isotemporal time reallocations were used to demonstrate the dose‐dependent associations between time use and outcomes. Beneficial associations with the outcomes were detected when sedentary time was reallocated to light PA, moderate‐to‐vigorous PA (MVPA), or sleep. For example, substituting 30 min of sedentary time with MVPA was associated with 7.2% (95% CI from −9.8% to −4.5%) lower visceral fat area, 4.9% (95% CI from −6.5% to −3.3%) lower body fat percentage, 1.6% (95% CI from −2.3% to −0.9%) smaller waist circumference, and 2.4% (95% CI from 1.2% to 3.5%) higher high‐density lipoprotein (HDL) cholesterol after accounting for gender, marital status, education level, employment, smoking, alcohol consumption, and sleep efficiency. Substituting sedentary time with sleep or light PA showed beneficial but smaller differences in adiposity measures and HDL cholesterol. Limiting sedentary time should be encouraged in adulthood.

中文翻译：

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可穿戴环测量的睡眠、久坐时间和体力活动与心脏代谢健康的关联：一种成分数据分析方法


一天 24 小时内的运动行为，包括体力活动 (PA)、久坐时间和睡眠，与心脏代谢健康相关。我们的目的是确定 24 小时运动构成与心脏代谢健康之间的关联，同时考虑睡眠效率。 1986 年芬兰北部出生队列研究中总共有 1134 名参与者，他们之前没有心血管疾病，他们提供了至少 4 天的 24 小时活动和睡眠效率，并通过可穿戴环进行了测量。通过生物阻抗评估参与者的身体成分，测量血压和腰围，并分析空腹血样中的脂质和葡萄糖。利用 24 小时运动成分和协变量（包括睡眠效率以及行为和社会经济因素）创建了心脏代谢结果的线性回归模型。等时时间重新分配用于证明时间使用和结果之间的剂量依赖性关联。当久坐时间重新分配为轻度 PA、中度至剧烈 PA (MVPA) 或睡眠时，检测到与结果的有益关联。例如，用 MVPA 代替 30 分钟的久坐时间，内脏脂肪面积降低 7.2%（95% CI 从 -9.8% 到 -4.5%），降低 4.9%（95% CI 从 -6.5% 到 -3.3%）考虑性别后，体脂百分比增加 1.6%（95% CI，-2.3% 至 -0.9%），腰围变小，高密度脂蛋白 (HDL) 胆固醇增加 2.4%（95% CI，1.2% 至 3.5%） 、婚姻状况、教育水平、就业、吸烟、饮酒和睡眠效率。用睡眠或轻度体力活动代替久坐时间，显示出有益的结果，但在肥胖指标和高密度脂蛋白胆固醇方面差异较小。成年后应鼓励限制久坐时间。