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Feel the breeze: Opening the therapeutic window with RIPTACs and induced proximity
Cell Chemical Biology ( IF 6.6 ) Pub Date : 2024-08-15 , DOI: 10.1016/j.chembiol.2024.07.013 Kyle Mangano 1 , Patrick Ryan Potts 2
中文翻译:
感受微风:用 RIPTAC 打开治疗窗口并诱导接近
更新日期:2024-08-15
Cell Chemical Biology ( IF 6.6 ) Pub Date : 2024-08-15 , DOI: 10.1016/j.chembiol.2024.07.013 Kyle Mangano 1 , Patrick Ryan Potts 2
Affiliation
In this issue of Cell Chemical Biology, Raina et al.1 demonstrate proof of concept of a new chemical induced proximity strategy for targeted cancer therapeutics. Building on a recent surge in induced proximity modalities, RIPTACs represent a novel approach that offers promise in treating cancers with improved safety profiles.
中文翻译:
感受微风:用 RIPTAC 打开治疗窗口并诱导接近
在本期《细胞化学生物学》中,Raina 等人。图 1展示了用于靶向癌症治疗的新化学诱导邻近策略的概念证明。基于最近激增的诱导接近模式,RIPTAC 代表了一种新方法,有望以更高的安全性来治疗癌症。