The perinatal period is marked by a higher risk of experiencing depressive, anxiety, and/or trauma-related symptoms, a phenomenon that affects millions of individuals each year. Obsessive-compulsive disorder (OCD) and posttraumatic stress disorder (PTSD) symptoms commonly co-occur but have rarely been examined together beyond prevalence estimates in the perinatal period. Our study aimed to explore patterns of associations among OCD and PTSD symptoms to elucidate within- and between-person effects and how these effects may change over time. Participants (N = 270) were recruited during pregnancy from an academic medical center affiliated with a midwestern university. PTSD, OCD, and depressive symptoms were assessed at pregnancy, 4, 8, and 12 weeks postpartum. A panel graphical vector autoregression model was used to estimate networks. The temporal network provided information regarding directed predictive effects between symptoms, and hyperarousal, neutralizing, and ordering were the most stable and predictive symptoms across time. The contemporaneous network, which yields undirected partial correlations between symptoms at a given moment, indicated that there were positive associations between intrusions and avoidance, hyperarousal and negative alterations in cognitions and mood, as well as between hyperarousal and dysphoria. This study identified hyperarousal and neutralizing as the PTSD and OCD symptoms with the strongest stability, predictive power, and association with other symptoms. Clinically, this indicates that screening for hyperarousal and neutralizing symptoms may identify individuals who could maximally benefit from treatment in the perinatal period. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

中文翻译：

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对整个围产期创伤后应激障碍和强迫症症状的小组网络分析。


围产期的特点是出现抑郁、焦虑和/或创伤相关症状的风险较高，这种现象每年影响数百万人。强迫症 (OCD) 和创伤后应激障碍 (PTSD) 症状通常同时出现，但除了围产期患病率估计值外，很少一起进行检查。我们的研究旨在探索强迫症和创伤后应激障碍症状之间的关联模式，以阐明人内和人与人之间的影响以及这些影响如何随着时间的推移而变化。参与者（N = 270）是在怀孕期间从中西部大学附属的学术医疗中心招募的。在怀孕时、产后 4、8 和 12 周评估 PTSD、OCD 和抑郁症状。使用面板图形向量自回归模型来估计网络。时间网络提供了有关症状之间的直接预测效应的信息，而过度唤醒、中和和排序是随时间变化最稳定和最具预测性的症状。同期网络在给定时刻的症状之间产生无向的部分相关性，表明侵入和回避、过度警觉和认知和情绪的消极改变之间以及过度警觉和烦躁之间存在正相关。这项研究将过度唤醒和中和视为具有最强稳定性、预测能力以及与其他症状关联的 PTSD 和 OCD 症状。在临床上，这表明筛查过度唤醒和中和症状可能会识别出可以最大程度地从围产期治疗中受益的个体。 （PsycInfo 数据库记录 (c) 2024 APA，保留所有权利）。