The perinatal period is marked by a higher risk of experiencing depressive, anxiety, and/or trauma-related symptoms, a phenomenon that affects millions of individuals each year. Obsessive-compulsive disorder (OCD) and posttraumatic stress disorder (PTSD) symptoms commonly co-occur but have rarely been examined together beyond prevalence estimates in the perinatal period. Our study aimed to explore patterns of associations among OCD and PTSD symptoms to elucidate within- and between-person effects and how these effects may change over time. Participants (N = 270) were recruited during pregnancy from an academic medical center affiliated with a midwestern university. PTSD, OCD, and depressive symptoms were assessed at pregnancy, 4, 8, and 12 weeks postpartum. A panel graphical vector autoregression model was used to estimate networks. The temporal network provided information regarding directed predictive effects between symptoms, and hyperarousal, neutralizing, and ordering were the most stable and predictive symptoms across time. The contemporaneous network, which yields undirected partial correlations between symptoms at a given moment, indicated that there were positive associations between intrusions and avoidance, hyperarousal and negative alterations in cognitions and mood, as well as between hyperarousal and dysphoria. This study identified hyperarousal and neutralizing as the PTSD and OCD symptoms with the strongest stability, predictive power, and association with other symptoms. Clinically, this indicates that screening for hyperarousal and neutralizing symptoms may identify individuals who could maximally benefit from treatment in the perinatal period. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

中文翻译：

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整个围产期创伤后应激障碍和强迫症症状的面板网络分析。


围产期的特点是出现抑郁、焦虑和/或创伤相关症状的风险较高，这种现象每年影响数百万人。强迫症 （OCD） 和创伤后应激障碍 （PTSD） 症状通常同时发生，但很少在围产期估计患病率之外一起进行检查。我们的研究旨在探索强迫症和 PTSD 症状之间的关联模式，以阐明人体内和人与人之间的影响以及这些影响如何随着时间的推移而变化。参与者 （N = 270） 是在怀孕期间从中西部大学附属的学术医学中心招募的。在怀孕、产后 4 、 8 和 12 周评估 PTSD 、 OCD 和抑郁症状。面板图形向量自回归模型用于估计网络。时间网络提供了有关症状之间定向预测作用的信息，而过度觉醒、中和和排序是随时间变化最稳定和预测性的症状。同时期网络在给定时刻症状之间产生无向偏相关，表明侵入与回避、认知和情绪的过度觉醒和消极改变以及过度觉醒与烦躁之间存在正相关。本研究将过度觉醒和中和确定为 PTSD 和 OCD 症状，具有最强的稳定性、预测能力以及与其他症状的相关性。在临床上，这表明筛查过度觉醒和中和症状可能会识别出可以从围产期治疗中获益最大的个体。（PsycInfo 数据库记录 （c） 2024 APA，保留所有权利）。