To report the cumulative incidence of complications and to describe refractive error and visual acuity (VA) outcomes in children undergoing secondary intraocular lens (IOL) implantation after previous surgery for nontraumatic cataract. Pediatric cataract registry. Eighty children (108 eyes: 60 bilateral, 48 unilateral) undergoing lensectomy at younger than 13 years of age. Annual data collection from medical record review through 5 years after lensectomy. Cumulative incidence of newly emergent complications after secondary IOL implantation; refractive error and VA by 5 years after lensectomy. Median follow-up after secondary IOL implantation was 2.7 years (interquartile range [IQR], 0.8–3.3 years; range, 0.6–5.0 years) for bilateral and 2.1 years (range, 0.5–6.4 years) for unilateral cases. A common complication after secondary IOL implantation was a glaucoma-related adverse event (GRAE; glaucoma or glaucoma suspect); the cumulative incidence was 17% (95% confidence interval [CI], 3%–29%) in bilateral cases and 12% (95% CI, 0%–23%) in unilateral cases. The cumulative incidence of surgery for visual axis opacification was 2% (95% CI, 0%–7%) for bilateral cases and 4% (95% CI, 0%–10%) for unilateral cases. The median prediction error within 90 days of implantation was 0.88 diopter (D; IQR, –0.50 to +3.00 D) less hyperopic than intended among 21 eyes for bilateral cases and 1.50 D (IQR, –0.25 to +2.38 D) less among 19 unilateral cases. The median spherical equivalent refractive error at 5 years (at a median of 5.1 years of age) in eyes receiving a secondary IOL was +0.50 D (IQR, –2.38 to +2.94 D) for 48 bilateral cases and +0.06 D (IQR, –2.25 to +0.75 D) for 22 unilateral cases. Median monocular VA at 5 years was 20/63 (IQR, 20/50–20/100) for bilateral cases (n = 42) and 20/400 (IQR, 20/160–20/800) for unilateral cases (n = 33). Eyes with secondary IOL implantation have a risk of developing new GRAEs. Five years after lensectomy (approximately 2.5 years after secondary IOL implantation), the average refractive error was less hyperopic than desired given the anticipated further myopic shift before refraction stabilizes. Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.

中文翻译：

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儿童无晶状体二次人工晶状体植入术后 3 年的并发症、视力和屈光不正


报告并发症的累积发生率并描述先前非外伤性白内障手术后接受二次人工晶状体 (IOL) 植入的儿童的屈光不正和视力 (VA) 结果。儿童白内障登记处。 80 名儿童（108 只眼睛：60 只双侧，48 只单侧）在 13 岁以下接受晶状体切除术。晶状体切除术后 5 年内每年从病历审查中收集数据。二次人工晶状体植入后新出现并发症的累积发生率；晶状体切除术后 5 年的屈光不正和 VA。二次 IOL 植入后的中位随访时间，双侧病例为 2.7 年（四分位距 [IQR]，0.8-3.3 年；范围，0.6-5.0 年），单侧病例为 2.1 年（范围，0.5-6.4 年）。二次人工晶状体植入后的常见并发症是青光眼相关不良事件（GRAE；青光眼或疑似青光眼）；双侧病例的累积发生率为 17%（95% 置信区间 [CI]，3%–29%），单侧病例的累积发生率为 12%（95% CI，0%–23%）。双侧视轴混浊手术的累积发生率为 2%（95% CI，0%–7%），单侧病例为 4%（95% CI，0%–10%）。植入后 90 天内的中位预测误差为 0.88 屈光度（D；IQR，–0.50 至 +3.00 D），其中 21 只眼睛的双侧病例比预期远视度数低，19 只眼睛的远视度数比预期低 1.50 D（IQR，–0.25 至 +2.38 D）单方面案件。接受二次 IOL 的眼睛在 5 年时（中位年龄为 5.1 岁）的中位球面等效屈光不正为 48 例双侧病例的 +0.50 D（IQR，–2.38 至 +2.94 D）和 +0.06 D（IQR， –2.25 至 +0.75 D)（22 个单侧案例）。 双侧病例 (n = 42) 5 年时的中位单眼 VA 为 20/63 (IQR, 20/50–20/100)，单侧病例 (n = 20/400) (IQR, 20/160–20/800) 33）。二次人工晶状体植入的眼睛有发生新的 GRAE 的风险。晶状体切除术后五年（二次人工晶状体植入后约 2.5 年），考虑到在屈光稳定之前预期会进一步近视变化，平均屈光不正远视程度低于预期。专有或商业披露可在本文末尾的脚注和披露中找到。