Aim To assess the primary reattachment rate (PARR) in pneumatic retinopexy (PnR) versus pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD) meeting the Pneumatic Retinopexy versus Vitrectomy for the Management of Primary Rhegmatogenous Retinal Detachment Outcomes Randomised Trial (PIVOT) criteria with a single break in detached retina. Methods A post hoc analysis of two clinical trials. To be included, patients with primary RRD had to meet PIVOT criteria but could have only one break in the detached retina. Patients with additional pathology in the attached retina were included in a secondary analysis. The primary outcome was PARR following PnR versus PPV at 1-year postoperatively. Results 162 patients were included. 53% (86/162) underwent PnR and 47% (76/162) had a PPV. 99% (85/86) and 86.8% (66/76) completed the 1-year follow-up visits in the PnR and PPV groups, respectively. PARR was 88.2% (75/85) in the PnR group and 90.9% (60/66) in the PPV group (p=0.6) with a mean postoperative logMAR best-corrected visual acuity of 0.19±0.25 versus 0.34±0.37 (Snellen 20/30 vs 20/44) (p=0.01) each in the PnR and PPV groups, respectively. In an additional analysis of patients who were also allowed to have any pathology in the attached retina, the PARR was 85% (91/107) and 91.6% (66/72) in the PnR and PPV groups, respectively (p=0.18). Conclusions PnR and PPV provide similar long-term PARR in a substantial proportion of patients meeting PIVOT criteria with only a single break in the detached retina. Therefore, in patients meeting these specific criteria, PnR is an appropriate first-line therapy as it offers superior functional outcomes without compromising PARR. All data relevant to the study are included in the article or uploaded as supplementary information.

中文翻译：

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充气性视网膜固定术与睫状体玻璃体切除术治疗单断裂孔源性视网膜脱离的再连接率


目的 评估充气性视网膜固定术 （PnR） 与睫状玻璃体切除术 （PPV） 治疗孔源性视网膜脱离 （RRD） 的初次再连接率 （PARR），满足充气性视网膜固定术与玻璃体切除术治疗原发性孔源性视网膜脱离结局随机试验 （PIVOT） 标准，视网膜脱离单次断裂。方法 对两项临床试验进行事后分析。要纳入原发性 RRD 患者必须满足 PIVOT 标准，但脱离的视网膜只能有一次断裂。附着视网膜有其他病变的患者被纳入二次分析。主要结局是术后 1 年 PnR 与 PPV 后的 PARR。结果 共纳入 162 例患者。53% （86/162） 接受了 PnR，47% （76/162） 接受了 PPV。PnR 组和 PPV 组分别为 99% （85/86） 和 86.8% （66/76） 完成了 1 年随访。PnR 组的 PARR 为 88.2% （75/85），PPV 组为 90.9% （60/66） （p=0.6），平均术后 logMAR 最佳矫正视力为 0.19±0.25 vs 0.34±0.37 （Snellen 20/30 vs 20/44） （p=0.01） 分别在 PnR 和 PPV 组中。在对还允许在附着视网膜中出现任何病变的患者的另一分析中，PnR 和 PPV 组的 PARR 分别为 85% （91/107） 和 91.6% （66/72） （p=0.18）。结论 PnR 和 PPV 在满足 PIVOT 标准的很大一部分患者中提供了相似的长期 PARR，脱离的视网膜只有一次断裂。因此，对于满足这些特定标准的患者，PnR 是合适的一线治疗，因为它在不影响 PARR 的情况下提供卓越的功能结果。与研究相关的所有数据都包含在文章中或作为补充信息上传。