Aim To assess the primary reattachment rate (PARR) in pneumatic retinopexy (PnR) versus pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD) meeting the Pneumatic Retinopexy versus Vitrectomy for the Management of Primary Rhegmatogenous Retinal Detachment Outcomes Randomised Trial (PIVOT) criteria with a single break in detached retina. Methods A post hoc analysis of two clinical trials. To be included, patients with primary RRD had to meet PIVOT criteria but could have only one break in the detached retina. Patients with additional pathology in the attached retina were included in a secondary analysis. The primary outcome was PARR following PnR versus PPV at 1-year postoperatively. Results 162 patients were included. 53% (86/162) underwent PnR and 47% (76/162) had a PPV. 99% (85/86) and 86.8% (66/76) completed the 1-year follow-up visits in the PnR and PPV groups, respectively. PARR was 88.2% (75/85) in the PnR group and 90.9% (60/66) in the PPV group (p=0.6) with a mean postoperative logMAR best-corrected visual acuity of 0.19±0.25 versus 0.34±0.37 (Snellen 20/30 vs 20/44) (p=0.01) each in the PnR and PPV groups, respectively. In an additional analysis of patients who were also allowed to have any pathology in the attached retina, the PARR was 85% (91/107) and 91.6% (66/72) in the PnR and PPV groups, respectively (p=0.18). Conclusions PnR and PPV provide similar long-term PARR in a substantial proportion of patients meeting PIVOT criteria with only a single break in the detached retina. Therefore, in patients meeting these specific criteria, PnR is an appropriate first-line therapy as it offers superior functional outcomes without compromising PARR. All data relevant to the study are included in the article or uploaded as supplementary information.

中文翻译：

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气动视网膜固定术与平坦部玻璃体切除术治疗单次孔源性视网膜脱离的再附着率


目的 评估气动视网膜固定术 (PnR) 与玻璃体切除术 (PPV) 治疗孔源性视网膜脱离 (RRD) 的初次再附着率 (PARR)，以满足气动视网膜固定术与玻璃体切除术治疗原发性孔源性视网膜脱离结果随机试验 (PIVOT) 的结果视网膜脱离一次破裂的标准。方法 对两项临床试验进行事后分析。要纳入其中，原发性 RRD 患者必须符合 PIVOT 标准，但视网膜脱落只能有一次断裂。附着视网膜有其他病变的患者被纳入二次分析。主要结局是术后 1 年 PnR 后的 PARR 与 PPV 的比较。结果纳入162名患者。 53% (86/162) 接受了 PnR，47% (76/162) 接受了 PPV。 PnR 组和 PPV 组分别有 99% (85/86) 和 86.8% (66/76) 完成了 1 年随访。 PnR 组的 PARR 为 88.2% (75/85)，PPV 组的 PARR 为 90.9% (60/66) (p=0.6)，术后平均 logMAR 最佳矫正视力分别为 0.19±0.25 和 0.34±0.37 (Snellen PnR 组和 PPV 组分别为 20/30 与 20/44) (p=0.01)。在对附着视网膜也允许有任何病变的患者进行的另一项分析中，PnR 组和 PPV 组的 PARR 分别为 85% (91/107) 和 91.6% (66/72) (p=0.18) 。结论 PnR 和 PPV 在大部分符合 PIVOT 标准且视网膜仅出现一次断裂的患者中提供了类似的长期 PARR。因此，对于满足这些特定标准的患者，PnR 是一种合适的一线治疗，因为它可以在不影响 PARR 的情况下提供卓越的功能结果。与研究相关的所有数据都包含在文章中或作为补充信息上传。