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Assessing the clinical utility of inertial sensors for home monitoring in Parkinson’s disease: a comprehensive review
npj Parkinson's Disease ( IF 6.7 ) Pub Date : 2024-08-20 , DOI: 10.1038/s41531-024-00755-6
Stefano Sapienza 1, 2 , Olena Tsurkalenko 1, 2, 3 , Marijus Giraitis 1, 2, 3 , Alan Castro Mejia 1, 2 , Gelani Zelimkhanov 1, 2, 3 , Isabel Schwaninger 1, 2 , Jochen Klucken 1, 2, 3
Affiliation  

This review screened 296 articles on wearable sensors for home monitoring of people with Parkinson’s Disease within the PubMed Database, from January 2017 to May 2023. A three-level maturity framework was applied for classifying the aims of 59 studies included: demonstrating technical efficacy, diagnostic sensitivity, or clinical utility. As secondary analysis, user experience (usability and patient adherence) was evaluated. The evidences provided by the studies were categorized and stratified according to the level of maturity. Our results indicate that approximately 75% of articles investigated diagnostic sensitivity, i.e. correlation of sensor-data with clinical parameters. Evidence of clinical utility, defined as improvement on health outcomes or clinical decisions after the use of the wearables, was found only in nine papers. A third of the articles included reported evidence of user experience. Future research should focus more on clinical utility, to facilitate the translation of research results within the management of Parkinson’s Disease.



中文翻译:


评估惯性传感器在帕金森病家庭监测中的临床效用:全面综述



该综述筛选了 PubMed 数据库中 2017 年 1 月至 2023 年 5 月期间关于用于家庭监测帕金森病患者的可穿戴传感器的 296 篇文章。应用了三级成熟度框架对 59 项研究的目标进行分类,包括:展示技术功效、诊断敏感性或临床实用性。作为二次分析,评估了用户体验(可用性和患者依从性)。研究提供的证据根据成熟度进行分类和分层。我们的结果表明,大约 75% 的文章研究了诊断敏感性,即传感器数据与临床参数的相关性。临床效用的证据(定义为使用可穿戴设备后健康结果或临床决策的改善)仅在九篇论文中找到。三分之一的文章包含了用户体验的报告证据。未来的研究应更多​​地关注临床实用性,以促进研究成果在帕金森病治疗中的转化。

更新日期:2024-08-21
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