INTRODUCTION This study examined the long-term effectiveness of cognitive behavioral therapy (CBT) (≥ 2 years after the end of therapy) in the routine care of youth (mean 11.95 years; SD = 3.04 years) with primary anxiety disorder (AD). METHODS Two hundred and ten children with any AD as a primary diagnosis and with any comorbidity were included in the "Kids Beating Anxiety (KibA)" clinical trial and received evidence-based CBT. Diagnoses, severity of diagnoses, and further dimensional outcome variables of symptoms and functioning were assessed before (baseline), after the last treatment session (POST), and at two follow-up (FU) assessments in the child and caregiver report: 6 months (6MONTHS-FU) and >2 years (mean 4.31; SD = 1.07 years) after the last treatment session (long-term FU). RESULTS At POST, 61.38% showed total remission of all and any ADs. At long-term FU, the remission rate was 63.64%. Compared to baseline, ratings of severity, anxiety, impairment/burden, and life quality improved significantly after CBT in child and caregiver report. All pre-post/FU improvements and global success ratings were stable in child (Pre-Post: Hedges' g = 3.57; Pre-6MONTHS-FU: Hedges' g = 3.43; Pre-LT-FU: Hedges' g = 2.34) and caregiver report (Pre-Post: Hedges' g = 2.00; Pre-6MONTHS-FU: Hedges' g = 2.31; Pre-LT-FU: Hedges' g = 2.31) across all POST- and FU-assessment points. Some outcomes showed further significant improvement, and no deterioration was found over the course of time. Effect sizes calculated in the present study correspond to, or even exceed, effect sizes reported in previous meta-analysis. CONCLUSIONS Stable long-term effects of "KibA" CBT for youth with ADs, comparable to those results from efficacy studies, were achieved in a routine practice setting by applying treatment manuals tested in randomized controlled trials. These findings are remarkable, as the patient group studied here consisted of an age group within the main risk phase of developing further mental disorders, and therefore an increase in new-onset anxiety and further mental disorders would be expected over the long time span studied here.

中文翻译：

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认知行为疗法在患有焦虑症的青少年的常规门诊护理中的长期有效性。


简介 本研究探讨了认知行为疗法 (CBT)（治疗结束后≥2 年）在患有原发性焦虑症 (AD) 的青少年（平均 11.95 岁；SD = 3.04 岁）常规护理中的长期有效性。方法 210 名以任何 AD 为主要诊断且患有任何合并症的儿童被纳入“儿童战胜焦虑 (KibA)”临床试验，并接受基于证据的 CBT。在儿童和护理人员报告中的前（基线）、最后一次治疗后（POST）以及两次随访（FU）评估时评估诊断、诊断的严重程度以及症状和功能的进一步维度结果变量：6个月最后一次治疗（长期 FU）后（6 个月-FU）和 >2 年（平均 4.31；SD = 1.07 年）。结果 术后，61.38% 的患者所有 AD 均得到完全缓解。长期 FU 缓解率为 63.64%。与基线相比，儿童和护理人员报告中 CBT 后严重程度、焦虑、损伤/负担和生活质量的评级显着改善。儿童的所有前/FU 改善和总体成功评级均稳定（术后前：Hedges' g = 3.57；前 6 个月-FU：Hedges' g = 3.43；前 LT-FU：Hedges' g = 2.34）以及护理人员报告（术后前：Hedges' g = 2.00；6MONTHS-FU 前：Hedges' g = 2.31；LT-FU 前：Hedges' g = 2.31）涵盖所有 POST 和 FU 评估点。一些结果显示出进一步的显着改善，并且随着时间的推移没有发现恶化。本研究中计算的效应大小相当于甚至超过之前荟萃分析中报告的效应大小。 结论 通过应用随机对照试验中测试的治疗手册，在常规实践环境中实现了“KibA”CBT 对 AD 青少年的稳定长期效果，与功效研究的结果相当。这些发现是值得注意的，因为这里研究的患者群体由处于进一步发展精神障碍的主要风险阶段的年龄组组成，因此，在这里研究的长期跨度内，预计新发焦虑和进一步精神障碍会增加。