Despite the high utility and widespread use of Cre driver lines, lack of Cre specificity, Cre-induced toxicity or poor experimental design can affect experimental results and conclusions. Such pitfalls must be considered before embarking on any Cre-based studies in metabolic research.

中文翻译：

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代谢中转基因 Cre 驱动因素的安全指南


尽管 Cre 驱动系具有很高的实用性和广泛使用，但缺乏 Cre 特异性、Cre 诱导的毒性或不良的实验设计可能会影响实验结果和结论。在代谢研究中进行任何基于 Cre 的研究之前，必须考虑到这些陷阱。