Sarcopenia can lead to more postoperative complications and poorer prognosis in patients with colorectal cancer; however there is limited research exploring the incidence and influencing factors of different stages of sarcopenia in patients with colorectal cancer. We investigated 312 patients with colorectal cancer. Sarcopenia was determined by measuring muscle mass, grip strength, and gait speed. According to the European Working Group on Sarcopenia in Older People (EWGSOP) 2010, patients were classified into four groups: nonsarcopenia, presarcopenia, sarcopenia, and severe sarcopenia. The incidence of sarcopenia and severe sarcopenia was 10.3% and 8.7%, respectively. Multivariate logistic regression analysis showed that age, TNM stage smoking history, total protein, upper arm circumference, waist circumference, and Patient-Generated Subjective Global Assessment (PG-SGA) score were independently associated with sarcopenia at different stages. This study suggests that routine data should be used to provide targeted care during hospitalization for patients with colorectal cancer in order to reduce the incidence of sarcopenia and improve prognosis.

中文翻译：

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结直肠癌患者肌肉减少症及其影响因素。


肌肉减少症会导致结直肠癌患者术后并发症增多，预后较差；然而，探索结直肠癌患者不同阶段肌少症的发生率和影响因素的研究有限。我们调查了 312 名结直肠癌患者。通过测量肌肉质量、握力和步态速度来确定肌肉减少症。根据 2010 年欧洲老年人肌肉减少症工作组 (EWGSOP)，患者被分为四组：非肌肉减少症、前期肌肉减少症、肌肉减少症和严重肌肉减少症。少肌症和重度少肌症的发生率分别为10.3%和8.7%。多因素logistic回归分析显示，年龄、TNM分期吸烟史、总蛋白、上臂围、腰围、患者主观整体评估（PG-SGA）评分与不同阶段的肌少症独立相关。本研究提示应利用常规数据对结直肠癌患者住院期间进行针对性护理，以降低肌少症的发生率，改善预后。