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Male fertility restoration: in vivo and in vitro stem cell–based strategies using cryopreserved testis tissue: a scoping review
Fertility and Sterility ( IF 6.6 ) Pub Date : 2024-07-09 , DOI: 10.1016/j.fertnstert.2024.07.010
Elena von Rohden 1 , Christian Fuglesang S Jensen 2 , Claus Yding Andersen 3 , Jens Sønksen 4 , Jens Fedder 5 , Jørgen Thorup 6 , Dana A Ohl 7 , Mikkel Fode 4 , Eva R Hoffmann 8 , Linn Salto Mamsen 9
Affiliation  

Advances in the treatment of childhood cancer have significantly improved survival rates, with more than 80% of survivors reaching adulthood. However, gonadotoxic cancer treatments endanger future fertility, and prepubertal males have no option to preserve fertility by sperm cryopreservation. In addition, boys with cryptorchidism are at risk of compromised fertility in adulthood.

中文翻译:


男性生育能力恢复:使用冷冻保存的睾丸组织的体内和体外干细胞策略:范围综述



儿童癌症治疗的进步显著提高了生存率,超过 80% 的幸存者已成年。然而,性腺毒性癌症治疗会危及未来的生育能力,青春期前的男性别无选择通过精子冷冻保存来保持生育能力。此外,患有隐睾症的男孩在成年后有生育能力受损的风险。
更新日期:2024-07-09
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