One of the main limitations of commercial production of algae is the cost of cultivation, largely attributed to the cost of the nutrients; hence, finding cheap alternative substrates has been a significant line of research in this field. The dairy industry produces large amounts of wastewater that might be used as a cost-effective nutrient alternative, containing lactose as a main carbon source, as well as other essential nutrients like nitrogen and phosphate. Nevertheless, just a few algal species of commercial value can grow on any organic carbon sources, and even less are able to utilize lactose. In this work we have identified a strain capable of utilizing lactose for growth, and have characterized its ability to accumulate metabolites of commercial interest under heterotrophic growth conditions. was capable to utilize lactose from dairy wastewater, and to accumulate several amino acids, dicarboxylic acids, such as tartaric acid and succinic acid, and triacylglycerols in heterotrophic conditions. These metabolites have applications in the food, feed, and pharmaceutical industries, and in the green chemical industry for the production of bio-based green polymers and biofuels. The significance of these findings for future product development is discussed.

中文翻译：

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能够同化乳糖并在乳制品废物上生长的副小球藻微藻菌株的选择和表征


藻类商业化生产的主要限制之一是培养成本，这很大程度上归因于营养物的成本；因此，寻找廉价的替代基质一直是该领域的一个重要研究方向。乳制品行业产生大量废水，这些废水可用作具有成本效益的营养替代品，其中含有乳糖作为主要碳源，以及氮和磷酸盐等其他必需营养素。然而，只有少数具有商业价值的藻类可以在任何有机碳源上生长，能够利用乳糖的藻类就更少了。在这项工作中，我们鉴定了一种能够利用乳糖生长的菌株，并表征了其在异养生长条件下积累具有商业价值的代谢物的能力。能够利用乳制品废水中的乳糖，并在异养条件下积累多种氨基酸、二羧酸（例如酒石酸和琥珀酸）以及三酰甘油。这些代谢物可应用于食品、饲料和制药行业，以及用于生产生物基绿色聚合物和生物燃料的绿色化学工业。讨论了这些发现对未来产品开发的重要性。