Lead toxicosis remains a concern in raptors, especially following feeding on carcasses sourced from hunting. Rapid diagnosis of lead exposure and easy field monitoring is desirable. The LeadCareII analytical system, validated for rapid diagnoses of lead toxicity in humans, has been described as a useful evaluation system in various species. For this study we attempt to validate the LeadCareII system in the Cape Vulture (CV) (). Blood samples from CV housed under captive conditions and low background lead exposure, were pooled and spiked with known concentrations of a lead standard (0–60 µg/dL). Samples were analyzed by the LeadCareII system and by ICP-MS. The final results showed that despite good linearity the LeadCareII system underestimated lead concentrations by up to 50 %. While the results can be corrected by the derived equation, this is not supported due to the large underestimations evident. The reason for the underestimation is presently unknown.

中文翻译：

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与使用纯标准品的 ICP-MS 相比，在海角兀鹫 (Gyps coprotheres) 中验证 Lead Care II 系统


铅中毒仍然是猛禽的一个问题，特别是在捕食狩猎尸体后。铅暴露的快速诊断和简单的现场监测是可取的。 LeadCareII 分析系统经过验证，可快速诊断人类铅毒性，被认为是多种物种的有用评估系统。在本研究中，我们尝试在 Cape Vulture (CV) () 中验证 LeadCareII 系统。汇集来自圈养条件下和低背景铅暴露条件下的 CV 的血液样本，并加入已知浓度的铅标准品 (0–60 µg/dL)。样品通过 LeadCareII 系统和 ICP-MS 进行分析。最终结果表明，尽管线性良好，LeadCareII 系统仍低估了铅浓度高达 50%。虽然结果可以通过推导方程进行校正，但由于明显的大幅低估，这一点不被支持。目前尚不清楚低估的原因。