Rational optimization of glycoprotein E (gE)-encoding mRNA for improved Varicella-zoster virus mRNA vaccine development,Emerging Microbes & Infections

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Rational optimization of glycoprotein E (gE)-encoding mRNA for improved Varicella-zoster virus mRNA vaccine development
Emerging Microbes & Infections ( IF 8.4 ) Pub Date : 2024-09-12 , DOI: 10.1080/22221751.2024.2392661
Lulu Huang _{1,

2} , Shun Zhang ₃ , Tongyi Zhao _{1,

2} , Ting Cai ₃ , Lingling Bu _{1,

2} , Zhenhua Di _{1,

2} , Yujie Zhang _{1,

2} , Chen Yang ₄ , Yong Yang _{1,

2,

5} , Ang Lin _{1,

2,

6}

Affiliation

mRNA platform holds promise for next-generation Varicella-zoster Virus (VZV) vaccine development due to its high potency at inducing strong T-cell response. Built upon the design of our 1st-generat...

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