Association of serum biomarkers with radiographic knee osteoarthritis, knee pain and function in a young, male, trauma-exposed population – Findings from the ADVANCE study,Osteoarthritis and Cartilage

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Association of serum biomarkers with radiographic knee osteoarthritis, knee pain and function in a young, male, trauma-exposed population – Findings from the ADVANCE study
Osteoarthritis and Cartilage ( IF 7.2 ) Pub Date : 2024-08-03 , DOI: 10.1016/j.joca.2024.07.016
Oliver O'Sullivan ₁ , Joanne Stocks ₂ , Susie Schofield ₃ , James Bilzon ₄ , Christopher J Boos ₅ , Anthony M J Bull ₆ , Nicola T Fear ₇ , Fiona E Watt ₈ , Alexander N Bennett ₉ , Stefan Kluzek ₁₀ , Ana M Valdes ₁₁

Affiliation

Academic Department of Military Rehabilitation (ADMR), Defence Medical Rehabilitation Centre (DMRC), Stanford Hall, Loughborough, UK; Academic Unit of Injury, Recovery and Inflammation Sciences, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, UK.
Academic Unit of Injury, Recovery and Inflammation Sciences, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, UK.
National Heart and Lung Institute, Imperial College London, London, UK.
Centre for Sport, Exercise and Osteoarthritis Research Versus Arthritis, University of Bath, Bath, UK; Department for Health, University of Bath, Bath, UK.
Academic Department of Military Rehabilitation (ADMR), Defence Medical Rehabilitation Centre (DMRC), Stanford Hall, Loughborough, UK; Faculty of Health & Social Sciences, Bournemouth University, Bournemouth, UK.
Centre for Blast Injury Studies, Department of Bioengineering, Imperial College London, London, UK.
Academic Department of Military Mental Health, King's College London, London, UK.
Department of Immunology and Inflammation, Imperial College London, London, UK; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
Academic Department of Military Rehabilitation (ADMR), Defence Medical Rehabilitation Centre (DMRC), Stanford Hall, Loughborough, UK; National Heart and Lung Institute, Imperial College London, London, UK.
Academic Unit of Injury, Recovery and Inflammation Sciences, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, UK; Centre for Sport, Exercise and Osteoarthritis Research Versus Arthritis, University of Nottingham, Nottingham, UK.
Nottingham NIHR Biomedical Research Centre, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, UK; Department of Twin Research & Genetic Epidemiology, King's College London, London, UK.

The ArmeD SerVices TrAuma RehabilitatioN OutComE (ADVANCE) study is investigating long-term combat-injury outcomes; this sub-study aims to understand the association of osteoarthritis (OA) biomarkers with knee radiographic OA (rOA), pain and function in this high-risk population for post-traumatic OA.

中文翻译：

血清生物标志物与年轻男性创伤暴露人群放射学膝骨关节炎、膝关节疼痛和功能的关系 – ADVANCE 研究结果

ArmeD Services TrAuma RehabilitatioN OutComE （ADVANCE）研究正在调查长期战斗损伤结果;本子研究旨在了解骨关节炎（OA）生物标志物与创伤后 OA 高危人群膝关节放射学 OA （rOA）、疼痛和功能的关系。

更新日期：2024-08-03

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