The PB2 I714S mutation influenced mammalian adaptation of the H3N2 canine influenza virus by interfering with nuclear import efficiency and RNP complex assembly,Emerging Microbes & Infections

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The PB2 I714S mutation influenced mammalian adaptation of the H3N2 canine influenza virus by interfering with nuclear import efficiency and RNP complex assembly
Emerging Microbes & Infections ( IF 8.4 ) Pub Date : 2024-08-14 , DOI: 10.1080/22221751.2024.2387439
Xueyun Li _{1,

2} , Tingting Jia ₁ , Kele Wang ₃ , Liangliang Wang ₁ , Lijuan Zhou ₁ , Mao Li ₁ , Wenfei Zhu ₄ , Yuelong Shu _{1,

5} , Yongkun Chen ₃

Affiliation

Avian influenza viruses (AIVs) are the origin of multiple mammal influenza viruses. The genetic determinants of AIVs adapted to humans have been widely elucidated, however, the molecular mechanism ...

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