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Response to PARP Inhibition in BARD1-Mutated Refractory Neuroblastoma
The New England Journal of Medicine ( IF 96.2 ) Pub Date : 2024-08-15 , DOI: 10.1056/nejmc2403316
Margaret Cupit-Link 1 , Kohei Hagiwara 1 , Matthew Nagy 2 , Selene C Koo 1 , Brent A Orr 1 , Eytan Ruppin 2 , John Easton 3 , Jinghui Zhang 3 , Sara M Federico 3
Affiliation  

Some neuroblastomas carry disabling mutations in BARD1, a homologous recombination repair gene. A child with refractory neuroblastoma and a BARD1 mutation had a sustained response after treatment w...

中文翻译:


BARD1 突变难治性神经母细胞瘤对 PARP 抑制的反应



一些神经母细胞瘤携带同源重组修复基因 BARD1 的失能突变。一名患有难治性神经母细胞瘤且患有 BARD1 突变的儿童在接受治疗后出现了持续的反应...
更新日期:2024-08-15
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