Fecal microbial transplantation (FMT) for inflammatory diseases or refractory immune checkpoint inhibitor therapy is less effective than for preventing recurrent Clostridioides difficile infection. This commentary outlines strategies to use biomarkers of successful FMT to guide newer approaches to restore microbial homeostasis in individuals with dysbiosis-mediated inflammation.

中文翻译：

---

微生物组修饰用于失调性疾病的个性化治疗

粪便微生物移植（FMT）治疗炎症性疾病或难治性免疫检查点抑制剂治疗的效果不如预防复发性艰难梭菌感染的效果。本评论概述了使用成功 FMT 的生物标志物来指导恢复微生物失调介导炎症个体微生物稳态的新方法的策略。