UV-Mediated Facile Fabrication of a Robust, Fully Renewable and Controllably Biodegradable Poly(lactic acid)-Based Covalent Adaptable Network,ACS Macro Letters

当前位置： X-MOL 学术 › ACS Macro Lett. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

UV-Mediated Facile Fabrication of a Robust, Fully Renewable and Controllably Biodegradable Poly(lactic acid)-Based Covalent Adaptable Network
ACS Macro Letters ( IF 5.1 ) Pub Date : 2024-08-12 , DOI: 10.1021/acsmacrolett.4c00377
Xiaobo Wei ₁ , Xiutao Zhang ₁ , Tianyu Chen ₁ , Jing Huang _{1,

2} , Ting Li ₁ , Xuhui Zhang ₁ , Shibo Wang ₁ , Weifu Dong ₁

Affiliation

A robust and fully biobased covalent adaptable network (CAN) that allows recyclability, biocompatibility, and controlled biodegradability is reported. The CAN was fabricated through a simple photo-cross-linking method, wherein low-molecular-weight poly(lactic acid) (∼3 kDa) was modified with end 1,2-dithiolane rings through a one-step Steglich esterification reaction with thioctic acid (TA). These incorporated 1,2-dithiolane rings undergo photoinduced ring-opening polymerization, thus enabling the cross-linking of poly(lactic acid) with abundant dynamic disulfide bonds. The resultant CAN demonstrates excellent transparency, effective UV-blocking capabilities below 320 nm, robust tensile strength (∼39 MPa), and superior dimensional stability at 80 °C, alongside attractive biocompatibility. Moreover, owing to the dynamic exchange and redox-responsiveness of disulfide bonds, the material can be recycled by hot-pressing and a reduction–oxidation process while also being capable of controllably biodegrading at the end of its lifecycle. Furthermore, it exhibits reconfigurable shape memory properties with fast recovery. This study elucidates a straightforward approach to fabricating multifunctional and sustainable polymer materials with potential applications in diverse fields such as packaging, coating, and biomedicine.

中文翻译：

紫外线介导的鲁棒、完全可再生和可控生物降解聚乳酸基共价适应性网络的简便制造

据报道，一种强大且完全基于生物的共价适应性网络（CAN）具有可回收性、生物相容性和受控的生物降解性。 CAN是通过一种简单的光交联方法制备的，其中通过与硫辛酸进行一步Steglich酯化反应，用末端1,2-二硫戊环修饰低分子量聚乳酸（~3 kDa）酸（TA）。这些掺入的 1,2-二硫戊环发生光诱导开环聚合，从而使聚乳酸能够与丰富的动态二硫键交联。由此产生的 CAN 具有出色的透明度、有效的 320 nm 以下紫外线阻挡能力、强大的拉伸强度 (∼39 MPa) 和 80 °C 下卓越的尺寸稳定性，以及有吸引力的生物相容性。此外，由于二硫键的动态交换和氧化还原响应性，该材料可以通过热压和还原氧化过程进行回收，同时还能够在其生命周期结束时进行可控的生物降解。此外，它还具有可重新配置的形状记忆特性和快速恢复能力。这项研究阐明了一种制造多功能和可持续聚合物材料的简单方法，该材料在包装、涂料和生物医学等不同领域具有潜在的应用前景。

更新日期：2024-08-12

点击分享查看原文

点击收藏

阅读更多本刊新发论文本刊介绍/投稿指南