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Wriggly woes: Helminths stirring up T cell trouble
Immunity ( IF 25.5 ) Pub Date : 2024-08-13 , DOI: 10.1016/j.immuni.2024.07.014 Carlos M Pondevida 1 , Atishay Jay 1 , Golnaz Vahedi 2
中文翻译:
蠕动的困境:蠕虫引发 T 细胞麻烦
更新日期:2024-08-13
Immunity ( IF 25.5 ) Pub Date : 2024-08-13 , DOI: 10.1016/j.immuni.2024.07.014 Carlos M Pondevida 1 , Atishay Jay 1 , Golnaz Vahedi 2
Affiliation
Understanding determinants of immune response variation is central to developing treatment options. Even et al. show that naive CD4+ T cell transcriptional heterogeneity is altered by helminth infection leading to impaired immune responses independent of commensals.
中文翻译:
蠕动的困境:蠕虫引发 T 细胞麻烦
了解免疫反应变化的决定因素对于制定治疗方案至关重要。甚至等人。表明幼稚 CD4 + T 细胞转录异质性因蠕虫感染而改变,导致独立于共生体的免疫反应受损。