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Sinonasal Squamous Cell Carcinoma with DEK::AFF2 Rearrangement: An Aggressive Cancer with Bland Morphology.
The American Journal of Surgical Pathology ( IF 4.5 ) Pub Date : 2024-08-12 , DOI: 10.1097/pas.0000000000002281 Aude Trinquet 1 , Marick Laé 2, 3 , Charles Lépine 4, 5 , Marie-Delphine Lanic 3 , Vanessa Lacheretz-Szablewski 1 , Caroline Shaar Chneker 6 , Jean-Michel Goujon 7 , Valentin Favier 8 , Valérie Costes-Martineau 1, 9
The American Journal of Surgical Pathology ( IF 4.5 ) Pub Date : 2024-08-12 , DOI: 10.1097/pas.0000000000002281 Aude Trinquet 1 , Marick Laé 2, 3 , Charles Lépine 4, 5 , Marie-Delphine Lanic 3 , Vanessa Lacheretz-Szablewski 1 , Caroline Shaar Chneker 6 , Jean-Michel Goujon 7 , Valentin Favier 8 , Valérie Costes-Martineau 1, 9
Affiliation
DEK::AFF2 squamous cell carcinoma is a recently described cancer entity, with 29 cases reported to date. Occasionally, these carcinomas appear deceptively indistinguishable; however, specific morphological and phenotypic features suggest the presence of this rearrangement. However, the prognostic value of this diagnosis remains unclear. We aimed to report a new case series with histological, molecular, and clinical features.
中文翻译:
伴有 DEK::AFF2 重排的鼻窦鳞状细胞癌:一种形态平淡的侵袭性癌症。
DEK::AFF2 鳞状细胞癌是最近报道的一种癌症实体,迄今已报道 29 例。有时,这些癌看起来难以区分;然而,特定的形态学和表型特征表明存在这种重排。然而,该诊断的预后价值仍不清楚。我们旨在报告具有组织学、分子学和临床特征的新病例系列。
更新日期:2024-08-12
中文翻译:
伴有 DEK::AFF2 重排的鼻窦鳞状细胞癌:一种形态平淡的侵袭性癌症。
DEK::AFF2 鳞状细胞癌是最近报道的一种癌症实体,迄今已报道 29 例。有时,这些癌看起来难以区分;然而,特定的形态学和表型特征表明存在这种重排。然而,该诊断的预后价值仍不清楚。我们旨在报告具有组织学、分子学和临床特征的新病例系列。