Whether high-frequency phase-locked oscillations facilitate integration (‘binding’) of information across widespread cortical areas is controversial. Here we show with intracranial electroencephalography that cortico-cortical co-ripples (~100-ms-long ~90 Hz oscillations) increase during reading and semantic decisions, at the times and co-locations when and where binding should occur. Fusiform wordform areas co-ripple with virtually all language areas, maximally from 200 to 400 ms post-word-onset. Semantically specified target words evoke strong co-rippling between wordform, semantic, executive and response areas from 400 to 800 ms, with increased co-rippling between semantic, executive and response areas prior to correct responses. Co-ripples were phase-locked at zero lag over long distances (>12 cm), especially when many areas were co-rippling. General co-activation, indexed by non-oscillatory high gamma, was mainly confined to early latencies in fusiform and earlier visual areas, preceding co-ripples. These findings suggest that widespread synchronous co-ripples may assist the integration of multiple cortical areas for sustained periods during cognition.

高频锁相振荡是否有助于在广泛的皮层区域整合（“绑定”）信息是有争议的。在这里，我们通过颅内脑电图显示，皮质-皮质共波纹（~100 毫秒长 ~90 Hz 振荡）在阅读和语义决策期间、在应该发生结合的时间和地点增加。梭形词形区域几乎与所有语言区域共涟漪，最大在单词出现后 200 到 400 毫秒。语义指定的目标词在 400 到 800 毫秒的词形、语义、执行和响应区域之间引起强烈的共波纹，在正确响应之前，语义、执行和响应区域之间的共波纹增加。同波纹在长距离 （>12 cm） 上以零滞后锁相，尤其是当许多区域同波纹时。以非振荡性高 γ 为索引的一般共激活主要局限于梭形的早期潜伏期和早期视觉区域，在共波纹之前。这些发现表明，广泛的同步共波纹可能有助于在认知过程中持续整合多个皮层区域。