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Food perception induces fast fragmentation of hepatic mitochondria
Trends in Endocrinology & Metabolism ( IF 11.4 ) Pub Date : 2024-06-18 , DOI: 10.1016/j.tem.2024.06.002 Arnaud Chevrollier 1 , Jérome Boursier 2 , Valérie Desquiret-Dumas 3
Trends in Endocrinology & Metabolism ( IF 11.4 ) Pub Date : 2024-06-18 , DOI: 10.1016/j.tem.2024.06.002 Arnaud Chevrollier 1 , Jérome Boursier 2 , Valérie Desquiret-Dumas 3
Affiliation
have recently shown that sensory food perception in mice integrated at the hypothalamus would be sufficient to suppress hepatic glucose production in a rapid mechanism involving a newly described AKT-dependent kinase pathway that engages mitochondrial fission dynamics. Exploiting this pathway could guide strategies to treat type 2 diabetes.
中文翻译:
食物感知导致肝线粒体快速破碎
最近表明,整合在下丘脑的小鼠的感官食物感知足以抑制肝脏葡萄糖的产生,其快速机制涉及新描述的参与线粒体裂变动力学的 AKT 依赖性激酶途径。利用这一途径可以指导治疗 2 型糖尿病的策略。
更新日期:2024-06-18
中文翻译:
食物感知导致肝线粒体快速破碎
最近表明,整合在下丘脑的小鼠的感官食物感知足以抑制肝脏葡萄糖的产生,其快速机制涉及新描述的参与线粒体裂变动力学的 AKT 依赖性激酶途径。利用这一途径可以指导治疗 2 型糖尿病的策略。