Global Prevalence, Clinical Characteristics, Surveillance, Treatment Allocation, and Outcomes of Alcohol-Associated Hepatocellular Carcinoma,Clinical Gastroenterology and Hepatology

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Global Prevalence, Clinical Characteristics, Surveillance, Treatment Allocation, and Outcomes of Alcohol-Associated Hepatocellular Carcinoma
Clinical Gastroenterology and Hepatology ( IF 11.6 ) Pub Date : 2024-07-08 , DOI: 10.1016/j.cgh.2024.06.026
Rebecca Wenling Zeng ₁ , Christen En Ya Ong ₁ , Elden Yen Hng Ong ₁ , Charlotte Hui Chung ₁ , Wen Hui Lim ₁ , Jieling Xiao ₁ , Pojsakorn Danpanichkul ₂ , Jia Hao Law ₃ , Nicholas Syn ₄ , Douglas Chee ₅ , Alfred Wei Chieh Kow ₆ , Sung Won Lee ₇ , Hirokazu Takahashi ₈ , Takumi Kawaguchi ₉ , Nobuharu Tamaki ₁₀ , Yock Young Dan ₁₁ , Atsushi Nakajima ₁₂ , Karn Wijarnpreecha ₁₃ , Mark D Muthiah ₁₁ , Mazen Noureddin ₁₄ , Rohit Loomba ₁₅ , George N Ioannou ₁₆ , Darren Jun Hao Tan ₁ , Cheng Han Ng ₁₇ , Daniel Q Huang ₁₁

Affiliation

Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Department of Internal Medicine, Chiang Mai University, Chiang Mai, Thailand.
Division of Hepatobiliary & Pancreatic Surgery, Department of Surgery, National University Hospital, Singapore.
Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Biostatistics & Modelling Domain, Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Division of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore.
Division of Hepatobiliary & Pancreatic Surgery, Department of Surgery, National University Hospital, Singapore; Division of Surgical Oncology, National University Cancer Institute, Singapore; National University Centre for Organ Transplantation, National University Health System, Singapore.
Division of Hepatology, Department of Internal Medicine, Catholic University of Korea, Seoul, Republic of Korea.
Liver Center, Saga University Hospital, Saga, Japan.
Department of Digestive Disease Information & Research, School of Medicine, Kurume University, Fukuoka, Japan.
Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Division of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore; National University Centre for Organ Transplantation, National University Health System, Singapore.
Graduate School of Medicine, Yokohama City University, Yokohama, Japan.
Division of Gastroenterology and Hepatology, Department of Medicine, University of Arizona College of Medicine, Phoenix, Arizona; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Banner University Medical Center, Phoenix, Arizona.
Houston Research Institute, Houston, Texas.
NAFLD Research Center, Division of Gastroenterology and Hepatology, Department of Medicine, University of California San Diego, La Jolla, California.
Division of Gastroenterology, Department of Medicine, Veterans Affairs Puget Sound Health Care System, Seattle, Washington; Division of Gastroenterology, Department of Medicine, University of Washington, Seattle, Washington.
Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Digestive Disease Information & Research, School of Medicine, Kurume University, Fukuoka, Japan.

Although the burden of alcohol-associated hepatocellular carcinoma (HCC) is increasing with rising alcohol consumption, clinical presentation and outcomes of alcohol-associated HCC have not been systematically assessed. We aimed to determine the prevalence, clinical characteristics, surveillance rates, treatment allocation, and outcomes of alcohol-associated HCC.

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