Heart failure (HF) with preserved ejection fraction (HFpEF) reflects half of all clinical HF yet has few therapies. Obesity and diabetes are now common comorbidities which have focused attention towards underlying myocardial metabolic defects. The profile of a major metabolic pathway, glycolytic intermediates and their regulating enzymes and ancillary pathways, remains unknown.

中文翻译：

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射血分数保留的人心力衰竭心肌中糖酵解代谢物及其调节蛋白的景观


射血分数保留的心力衰竭 （HF） （HFpEF） 反映了所有临床 HF 的一半，但治疗方法很少。肥胖和糖尿病现在是常见的合并症，人们关注潜在的心肌代谢缺陷。主要代谢途径、糖酵解中间体及其调节酶和辅助途径的概况仍然未知。