INTRODUCTION Myriad treatment barriers prevent birthing parents with postpartum depression (PPD) from receiving timely treatment. We aimed to determine whether a peer-delivered online 1-day cognitive behavioral therapy (CBT)-based workshop added to treatment as usual (TAU) improves PPD and its comorbidities and is more cost-effective than TAU alone. METHODS This parallel-group, randomized controlled trial took place in Ontario, Canada (June 7, 2021, to February 18, 2022). Participants were ≥18 years old, had an infant ≤12 months old, and an Edinburgh Postnatal Depression Scale (EPDS) score ≥10. Participants were allocated to receive the workshop plus TAU (n = 202) or TAU and waitlisted to complete the workshop 12 weeks later (n = 203). The primary outcome was change in PPD (EPDS score) from enrollment to 12 weeks later. The secondary outcome was cost-effectiveness and tertiary outcomes included anxiety, social support, partner relationship quality, the mother-infant relationship, parenting stress, and infant temperament. RESULTS Participants had a mean age of 32.3 years (SD = 4.30) and 65% were White. The workshop led to a significant reduction in EPDS scores (15.95-11.37; d = 0.92, p < 0. 01) and was associated with higher odds of exhibiting a clinically significant decrease in EPDS scores (OR = 2.03; 95% CI: 1.26-3.29). The workshop plus TAU was more cost-effective than TAU alone. It also led to improvements in postpartum anxiety, infant-focused anxiety, parenting stress, and infant temperament. CONCLUSIONS Peer-delivered 1-day CBT-based workshops can improve PPD and are a potentially scalable low-intensity treatment that could help increase treatment access.

中文翻译：

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为期一天的同伴交付的基于认知行为治疗的产后抑郁症研讨会：一项随机对照试验。


引言 无数的治疗障碍阻碍了患有产后抑郁症 (PPD) 的亲生父母及时接受治疗。我们的目的是确定在常规治疗 (TAU) 基础上加入同行提供的为期 1 天的基于认知行为治疗 (CBT) 的在线研讨会是否可以改善 PPD 及其合并症，并且比单独使用 TAU 更具成本效益。方法 这项平行组随机对照试验在加拿大安大略省进行（2021年6月7日至2022年2月18日）。参与者年龄≥18岁，婴儿≤12个月，爱丁堡产后抑郁量表（EPDS）评分≥10。参与者被分配接受研讨会加 TAU (n = 202) 或 TAU 并列入候补名单以在 12 周后完成研讨会 (n = 203)。主要结局是从入组到 12 周后的 PPD（EPDS 评分）变化。第二个结果是成本效益，第三个结果包括焦虑、社会支持、伴侣关系质量、母婴关系、养育压力和婴儿气质。结果 参与者的平均年龄为 32.3 岁 (SD = 4.30)，其中 65% 是白人。该研讨会导致 EPDS 评分显着降低（15.95-11.37；d = 0.92，p < 0. 01），并且与 EPDS 评分出现临床显着降低的可能性较高相关（OR = 2.03；95% CI：1.26 -3.29）。研讨会加上 TAU 比单独使用 TAU 更具成本效益。它还改善了产后焦虑、以婴儿为中心的焦虑、育儿压力和婴儿气质。结论 同伴提供的为期 1 天的基于 CBT 的研讨会可以改善 PPD，并且是一种潜在可扩展的低强度治疗，有助于增加治疗机会。