In this paper is explored the application of optical fibre-based dosimetry in the context of charged-particles MiniBeam Radiation Therapy through comprehensive simulation analyses. A FLUKA simulation of 64 Scintillating Plastic Optical Fibre array was implemented based on a prototype built in our group. The simulations indicate that the proposed system accurately reproduces the peak-and-valley pattern of minibeams. The optical photons transport inside and between fibres was also simulated, revealing that the optical crosstalk is negligible. The resilience of the detector’s electronics under secondary radiation composed of photons and neutrons was assessed. Our results suggest the electronics’ ability to withstand the expected radiation environment in clinical accelerators. This simulation-based investigation provides valuable insights into the feasibility of optical fibre-based dosimetry for MBRT. The results show the potential of using an array of thin scintillating plastic optical fibres to determine the peak–valley dose ratio, which is a key parameter to assess the efficacy of this emerging modality.

中文翻译：

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质子微束闪烁纤维剂量测定的主要模拟研究


本文通过全面的模拟分析，探讨了基于光纤的剂量测定法在带电粒子 MiniBeam 放射治疗中的应用。基于我们小组构建的原型，实现了 64 个闪烁塑料光纤阵列的 FLUKA 模拟。仿真结果表明，所提出的系统准确地再现了微光束的峰谷模式。还模拟了光纤内部和光纤之间的光学光子传输，揭示了光学串扰可以忽略不计。评估了探测器电子设备在由光子和中子组成的二次辐射下的弹性。我们的结果表明，该电子设备能够承受临床加速器中预期的辐射环境。这项基于模拟的研究为基于光纤的剂量测定用于 MBRT 的可行性提供了宝贵的见解。结果显示了使用一系列薄闪烁塑料光纤来确定峰谷剂量比的潜力，这是评估这种新兴模式疗效的关键参数。