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Navigating the evolving landscape of atopic dermatitis: Challenges and future opportunities: The 4th Davos declaration
Allergy ( IF 12.6 ) Pub Date : 2024-08-05 , DOI: 10.1111/all.16247 Claudia Traidl‐Hoffmann 1, 2, 3 , Jamie Afghani 1 , Cezmi Akdis 3, 4 , Mübecel Akdis 4 , Handan Aydin 5 , Katja Bärenfaller 4 , Heidrun Behrendt 6 , Thomas Bieber 3, 7 , Paul Bigliardi 8 , Mei Bigliardi‐Qi 8 , Charlotte Menné Bonefeld 9 , Stefanie Bösch 10, 11 , Marie Charlotte Brüggen 3, 10, 11 , Sebastian Diemert 12 , Hans‐Werner Duchna 3, 13 , Martina Fähndrich 14 , Danielle Fehr 3, 10, 11 , Marc Fellmann 15 , Remo Frei 3, 16, 17 , Lena H. Garvey 18, 19 , Raschid Gharbo 20 , Mehmet Gökkaya 1, 2 , Karin Grando 3, 10, 11 , Carole Guillet 10, 11 , Erman Guler 21 , Jan Gutermuth 22 , Nadine Herrmann 23 , Dirk Jan Hijnen 24 , Claudia Hülpüsch 1, 2, 3 , Alan D. Irvine 25 , Erika Jensen‐Jarolim 26, 27 , Heidi H. Kong 28 , Hillel Koren 29 , Claudia C. V. Lang 3, 9, 10 , Roger Lauener 30 , Laura Maintz 23 , Pierre‐Yves Mantel 3 , Emanuel Maverakis 31 , Matthias Möhrenschlager 13 , Svenja Müller 23 , Kari Nadeau 32 , Avidan U. Neumann 1, 2 , Liam O'Mahony 33, 34 , Fahafahantsoa Rapelanoro Rabenja 35 , Harald Renz 36 , Claudio Rhyner 3 , Ernst Rietschel 3 , Johannes Ring 37 , Caroline Roduit 16, 30 , Mari Sasaki 16 , Mirjam Schenk 3, 38 , Jens Schröder 39 , Dagmar Simon 40 , Hans‐Uwe Simon 41, 42 , Milena Sokolowska 3, 4 , Sonja Ständer 43 , Martin Steinhoff 44, 45, 46, 47, 48 , Doris Straub Piccirillo 3 , Alain Taïeb 49 , Roberto Takaoka 50 , Martin Tapparo 51 , Henrique Teixeira 22 , Jacob Pontoppidan Thyssen 52 , Stephan Traidl 53, 54 , Miriam Uhlmann 3 , Willem van de Veen 4 , Marianne van Hage 55 , Christian Virchow 56 , Andreas Wollenberg 57, 58, 59 , Mitamura Yasutaka 4 , Alexander Zink 60, 61 , Peter Schmid‐Grendelmeier 3, 9, 10
Allergy ( IF 12.6 ) Pub Date : 2024-08-05 , DOI: 10.1111/all.16247 Claudia Traidl‐Hoffmann 1, 2, 3 , Jamie Afghani 1 , Cezmi Akdis 3, 4 , Mübecel Akdis 4 , Handan Aydin 5 , Katja Bärenfaller 4 , Heidrun Behrendt 6 , Thomas Bieber 3, 7 , Paul Bigliardi 8 , Mei Bigliardi‐Qi 8 , Charlotte Menné Bonefeld 9 , Stefanie Bösch 10, 11 , Marie Charlotte Brüggen 3, 10, 11 , Sebastian Diemert 12 , Hans‐Werner Duchna 3, 13 , Martina Fähndrich 14 , Danielle Fehr 3, 10, 11 , Marc Fellmann 15 , Remo Frei 3, 16, 17 , Lena H. Garvey 18, 19 , Raschid Gharbo 20 , Mehmet Gökkaya 1, 2 , Karin Grando 3, 10, 11 , Carole Guillet 10, 11 , Erman Guler 21 , Jan Gutermuth 22 , Nadine Herrmann 23 , Dirk Jan Hijnen 24 , Claudia Hülpüsch 1, 2, 3 , Alan D. Irvine 25 , Erika Jensen‐Jarolim 26, 27 , Heidi H. Kong 28 , Hillel Koren 29 , Claudia C. V. Lang 3, 9, 10 , Roger Lauener 30 , Laura Maintz 23 , Pierre‐Yves Mantel 3 , Emanuel Maverakis 31 , Matthias Möhrenschlager 13 , Svenja Müller 23 , Kari Nadeau 32 , Avidan U. Neumann 1, 2 , Liam O'Mahony 33, 34 , Fahafahantsoa Rapelanoro Rabenja 35 , Harald Renz 36 , Claudio Rhyner 3 , Ernst Rietschel 3 , Johannes Ring 37 , Caroline Roduit 16, 30 , Mari Sasaki 16 , Mirjam Schenk 3, 38 , Jens Schröder 39 , Dagmar Simon 40 , Hans‐Uwe Simon 41, 42 , Milena Sokolowska 3, 4 , Sonja Ständer 43 , Martin Steinhoff 44, 45, 46, 47, 48 , Doris Straub Piccirillo 3 , Alain Taïeb 49 , Roberto Takaoka 50 , Martin Tapparo 51 , Henrique Teixeira 22 , Jacob Pontoppidan Thyssen 52 , Stephan Traidl 53, 54 , Miriam Uhlmann 3 , Willem van de Veen 4 , Marianne van Hage 55 , Christian Virchow 56 , Andreas Wollenberg 57, 58, 59 , Mitamura Yasutaka 4 , Alexander Zink 60, 61 , Peter Schmid‐Grendelmeier 3, 9, 10
Affiliation
The 4th Davos Declaration was developed during the Global Allergy Forum in Davos which aimed to elevate the care of patients with atopic dermatitis (AD) by uniting experts and stakeholders. The forum addressed the high prevalence of AD, with a strategic focus on advancing research, treatment, and management to meet the evolving challenges in the field. This multidisciplinary forum brought together top leaders from research, clinical practice, policy, and patient advocacy to discuss the critical aspects of AD, including neuroimmunology, environmental factors, comorbidities, and breakthroughs in prevention, diagnosis, and treatment. The discussions were geared towards fostering a collaborative approach to integrate these advancements into practical, patient‐centric care. The forum underlined the mounting burden of AD, attributing it to significant environmental and lifestyle changes. It acknowledged the progress in understanding AD and in developing targeted therapies but recognized a gap in translating these innovations into clinical practice. Emphasis was placed on the need for enhanced awareness, education, and stakeholder engagement to address this gap effectively and to consider environmental and lifestyle factors in a comprehensive disease management strategy. The 4th Davos Declaration marks a significant milestone in the journey to improve care for people with AD. By promoting a holistic approach that combines research, education, and clinical application, the Forum sets a roadmap for stakeholders to collaborate to improve patient outcomes in AD, reflecting a commitment to adapt and respond to the dynamic challenges of AD in a changing world.
中文翻译：
应对特应性皮炎不断演变的格局：挑战和未来机遇：第四届达沃斯宣言
第四届达沃斯宣言是在达沃斯全球过敏论坛期间制定的，旨在通过联合专家和利益相关者来提高特应性皮炎 (AD) 患者的护理水平。该论坛讨论了 AD 的高患病率，战略重点是推进研究、治疗和管理，以应对该领域不断变化的挑战。这个多学科论坛汇集了来自研究、临床实践、政策和患者倡导的顶尖领导者，讨论 AD 的关键方面，包括神经免疫学、环境因素、合并症以及预防、诊断和治疗方面的突破。讨论旨在促进一种协作方法，将这些进步整合到实际的、以患者为中心的护理中。该论坛强调了 AD 所带来的日益沉重的负担，并将其归因于环境和生活方式的重大变化。它承认在理解 AD 和开发靶向治疗方面取得的进展，但也认识到将这些创新转化为临床实践方面存在差距。强调需要加强认识、教育和利益相关者参与，以有效解决这一差距，并在综合疾病管理策略中考虑环境和生活方式因素。第四届达沃斯宣言标志着改善 AD 患者护理历程中的一个重要里程碑。通过推广结合研究、教育和临床应用的整体方法，论坛为利益相关者制定了合作改善 AD 患者治疗结果的路线图，体现了在不断变化的世界中适应和应对 AD 动态挑战的承诺。
更新日期：2024-08-05
中文翻译：
应对特应性皮炎不断演变的格局：挑战和未来机遇：第四届达沃斯宣言
第四届达沃斯宣言是在达沃斯全球过敏论坛期间制定的，旨在通过联合专家和利益相关者来提高特应性皮炎 (AD) 患者的护理水平。该论坛讨论了 AD 的高患病率，战略重点是推进研究、治疗和管理，以应对该领域不断变化的挑战。这个多学科论坛汇集了来自研究、临床实践、政策和患者倡导的顶尖领导者，讨论 AD 的关键方面，包括神经免疫学、环境因素、合并症以及预防、诊断和治疗方面的突破。讨论旨在促进一种协作方法，将这些进步整合到实际的、以患者为中心的护理中。该论坛强调了 AD 所带来的日益沉重的负担，并将其归因于环境和生活方式的重大变化。它承认在理解 AD 和开发靶向治疗方面取得的进展，但也认识到将这些创新转化为临床实践方面存在差距。强调需要加强认识、教育和利益相关者参与，以有效解决这一差距，并在综合疾病管理策略中考虑环境和生活方式因素。第四届达沃斯宣言标志着改善 AD 患者护理历程中的一个重要里程碑。通过推广结合研究、教育和临床应用的整体方法，论坛为利益相关者制定了合作改善 AD 患者治疗结果的路线图，体现了在不断变化的世界中适应和应对 AD 动态挑战的承诺。
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