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A biodegradable and self-deployable electronic tent electrode for brain cortex interfacing
Nature Electronics ( IF 33.7 ) Pub Date : 2024-08-05 , DOI: 10.1038/s41928-024-01216-x
Jae-Young Bae , Gyeong-Seok Hwang , Young-Seo Kim , Jooik Jeon , Minseong Chae , Joon-Woo Kim , Sian Lee , Seongchan Kim , Soo-Hwan Lee , Sung-Geun Choi , Ju-Yong Lee , Jae-Hwan Lee , Kyung-Sub Kim , Joo-Hyeon Park , Woo-Jin Lee , Yu-Chan Kim , Kang-Sik Lee , Jeonghyun Kim , Hyojin Lee , Jung Keun Hyun , Ju-Young Kim , Seung-Kyun Kang

High-density, large-area electronic interfaces are a key component of brain–computer interface technologies. However, current designs typically require patients to undergo invasive procedures, which can lead to various complications. Here, we report a biodegradable and self-deployable tent electrode for brain cortex interfacing. The system can be integrated with multiplexing arrays and a wireless module for near-field communication and data transfer. It can be programmably packaged and self-deployed using a syringe for minimally invasive delivery through a small hole. Following delivery, it can expand to cover an area around 200 times its initial size. The electrode also naturally decomposes within the body after use, minimizing the impact of subsequent removal surgery. Through in vivo demonstrations, we show that our cortical-interfacing platform can be used to stimulate large populations of cortical activities.



中文翻译:


用于大脑皮层接口的可生物降解且可自部署的电子帐篷电极



高密度、大面积电子接口是脑机接口技术的关键组成部分。然而,当前的设计通常要求患者接受侵入性手术,这可能会导致各种并发症。在这里,我们报告了一种可生物降解且可自部署的帐篷电极,用于大脑皮层接口。该系统可以与多路复用阵列和无线模块集成,用于近场通信和数据传输。它可以通过编程进行包装,并使用注射器自行部署,通过小孔进行微创输送。交付后,它可以扩展到覆盖其初始大小约 200 倍的区域。电极在使用后也会在体内自然分解,从而最大限度地减少后续切除手术的影响。通过体内演示,我们展示了我们的皮质接口平台可用于刺激大量皮质活动。

更新日期:2024-08-05
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