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Optogenetic modulation of cardiac autonomic nervous system
Autonomic Neuroscience ( IF 3.2 ) Pub Date : 2024-07-17 , DOI: 10.1016/j.autneu.2024.103199
Ramon A Hernández-Domínguez 1 , Jorge F Herrera-Orozco 2 , Guadalupe E Salazar-Calderón 3 , María Chávez-Canales 4 , Manlio F Márquez 2 , Felipe González-Álvarez 3 , Armando Totomoch-Serra 2 , Tania Reyes-Cruz 5 , Finn Lip 3 , José J Aceves-Buendía 3
Affiliation  

The following is a narrative review of the fundamentals of optogenetics. It focuses on the advantages and constraints of manipulating the autonomic nervous system by modifying the pathophysiological characteristics that arise in different diseases. Although the use of this technique is currently experimental, we will discuss improvements that have been implemented and identify the necessary measures for potential preclinical translation in the control of the cardiac autonomic nervous system.

中文翻译:


心脏自主神经系统的光遗传学调节



以下是对光遗传学基础知识的叙述性回顾。它侧重于通过改变不同疾病中出现的病理生理学特征来操纵自主神经系统的优点和局限性。尽管该技术的使用目前处于实验阶段,但我们将讨论已实施的改进,并确定控制心脏自主神经系统的潜在临床前转化的必要措施。
更新日期:2024-07-17
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