Background Biomass burning (BB) is a major source of air pollution and particulate matter (PM) in Southeast Asia. However, the health effects of PM smaller than 10 µm (PM10) originating from BB may differ from those of other sources. This study aimed to estimate the short-term association of PM10 from BB with respiratory and cardiovascular hospital admissions in Peninsular Malaysia, a region often exposed to BB events. Methods We obtained and analyzed daily data on hospital admissions, PM10 levels and BB days from five districts from 2005 to 2015. We identified BB days by evaluating the BB hotspots and backward wind trajectories. We estimated PM10 attributable to BB from the excess of the moving average of PM10 during days without BB hotspots. We fitted time-series quasi-Poisson regression models for each district and pooled them using meta-analyses. We adjusted for potential confounders and examined the lagged effects up to 3 days, and potential effect modification by age and sex. Results We analyzed 210 960 respiratory and 178 952 cardiovascular admissions. Almost 50% of days were identified as BB days, with a mean PM10 level of 53.1 µg/m3 during BB days and 40.1 µg/m3 during normal days. A 10 µg/m3 increment in PM10 from BB was associated with a 0.44% (95% CI: 0.06, 0.82%) increase in respiratory admissions at lag 0–1, with a stronger association in adults aged 15–64 years and females. We did not see any significant associations for cardiovascular admissions. Conclusions Our findings suggest that short-term exposure to PM10 from BB increased the risk of respiratory hospitalizations in Peninsular Malaysia.

中文翻译：

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马来西亚半岛因生物质燃烧而导致的 PM10 与呼吸系统和心血管系统入院的短期关联


背景 生物质燃烧（BB）是东南亚空气污染和颗粒物（PM）的主要来源。然而，源自 BB 的小于 10 µm (PM10) 的 PM 对健康的影响可能与其他来源的不同。本研究旨在评估马来西亚半岛（该地区经常发生BB事件）中BB引起的PM10与呼吸系统和心血管疾病住院的短期关联。方法 获取并分析 2005 年至 2015 年五个地区的住院人数、PM10 水平和 BB 天数的每日数据。通过评估 BB 热点和逆向风轨迹来识别 BB 天。我们根据没有 BB 热点的日子里 PM10 移动平均值的超额估计了 BB 造成的 PM10。我们为每个地区拟合了时间序列准泊松回归模型，并使用荟萃分析将它们汇总。我们调整了潜在的混杂因素，并检查了长达 3 天的滞后效应，以及年龄和性别的潜在效应修正。结果 我们分析了 210 960 例呼吸系统入院病例和 178 952 例心血管入院病例。近 50% 的日子被确定为 BB 天，BB 日的平均 PM10 水平为 53.1 µg/m3，正常日为 40.1 µg/m3。 BB 中的 PM10 每增加 10 µg/m3，与滞后 0-1 时呼吸系统入院率增加 0.44%（95% CI：0.06，0.82%）相关，其中与 15-64 岁成人和女性的相关性更强。我们没有发现与心血管疾病入院有任何显着关联。结论 我们的研究结果表明，短期接触 BB 产生的 PM10 会增加马来西亚半岛因呼吸系统疾病住院的风险。