Approximately 1% of the UK population take oral corticosteroids for ≥ 28 days each year, for broadly two reasons: deficiency in corticosteroid requiring replacement; or therapeutic corticosteroid for inflammatory conditions. Acute deficiency can occur at times of physiological stress (e.g. surgery), potentially leading to major complications. The Association of Anaesthetists' 2020 consensus guideline provides detailed advice for the management of glucocorticoids during the peri-operative period for patients with adrenal insufficiency. This national audit aimed to assess compliance with this guideline.

中文翻译：

---

围手术期外源性类固醇替代 (PREdS)：对目前服用治疗类固醇的患者围手术期处方进行的国家审计


大约 1% 的英国人口每年服用口服皮质类固醇 ≥ 28 天，大致有两个原因： 皮质类固醇缺乏，需要补充；或治疗性皮质类固醇治疗炎症。急性缺乏症可能发生在生理压力（例如手术）时，可能导致严重并发症。麻醉师协会2020年共识指南为肾上腺功能不全患者围手术期糖皮质激素的管理提供了详细建议。此次国家审计旨在评估对该指南的遵守情况。