Purpose Our aim was to describe the visual outcomes and determine the clinical factors in ischaemic retinal vasculitis (IRV) that were predictive of a poor visual prognosis or infectious aetiology. Methods Retrospective cohort study of consecutive presentations of IRV to Auckland District Health Board from 2009 to 2022. Results The median age at presentation was 39.2 years and 108 (53.7%) were women. The total median follow-up was 4.8 years. Infectious aetiology was present in 151 eyes (52.1%). Moderate visual loss (20/50 to 20/200) occurred in 20 eyes (6.9%) and severe visual loss (≤20/200) occurred in 41 eyes (14.1%). Median visual acuity was 20/30 (IQR 20/25 to 20/100) on presentation and 20/25 (IQR 20/20 to 20/50) at final follow-up. Retinitis (HR 4.675 p=0.048) and cystoid macular oedema (CME) (HR 7.265 p<0.001) were significantly associated with vision loss. There was concurrent macular ischaemia in 26 eyes (19.4%) and CME in 52 eyes (17.9%). Retinitis was predictive of infectious aetiology (p=0.006) and cotton wool spots for non-infectious aetiology (p<0.001). Retinal haemorrhage (HR 5.580 p=0.001), retinal vein occlusion (HR 5.071 p=0.001) and quadrants of ischaemia (HR 2.222 p=0.025) were significantly associated with vitreous haemorrhage. Conclusion In patients with IRV, 21% of affected individuals sustained moderate-to-severe vision loss over 5 years. Ultra-widefield fluorescein angiography can be used to quantify the risk of neovascular complications and guide treatment. Data are available upon reasonable request. Not applicable.

中文翻译：

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缺血性视网膜血管炎的视力结果和预后因素


目的 我们的目的是描述缺血性视网膜血管炎 (IRV) 的视觉结果并确定可预测不良视力预后或感染性病因的临床因素。方法 对 2009 年至 2022 年连续向奥克兰地区卫生局提出 IRV 的回顾性队列研究。结果 就诊时的中位年龄为 39.2 岁，其中 108 名 (53.7%) 为女性。总中位随访时间为 4.8 年。 151 只眼睛 (52.1%) 存在感染性病因。 20只眼（6.9%）出现中度视力丧失（20/50至20/200），41只眼（14.1%）出现重度视力丧失（≤20/200）。就诊时的中位视力为 20/30（IQR 20/25 至 20/100），最终随访时的中位视力为 20/25（IQR 20/20 至 20/50）。视网膜炎（HR 4.675 p=0.048）和黄斑囊样水肿（CME）（HR 7.265 p<0.001）与视力丧失显着相关。 26只眼（19.4%）并发黄斑缺血，52只眼（17.9%）并发CME。视网膜炎可预测感染性病因（p=0.006），棉絮斑可预测非感染性病因（p<0.001）。视网膜出血（HR 5.580 p=0.001）、视网膜静脉阻塞（HR 5.071 p=0.001）和象限缺血（HR 2.222 p=0.025）与玻璃体出血显着相关。结论 在 IRV 患者中，21% 的患者在 5 年内出现中度至重度视力丧失。超宽视野荧光素血管造影可用于量化新生血管并发症的风险并指导治疗。数据可根据合理要求提供。不适用。