Left ventricular volume and maximal functional capacity in heart failure with preserved ejection fraction: Size matters,European Journal of Heart Failure

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Left ventricular volume and maximal functional capacity in heart failure with preserved ejection fraction: Size matters
European Journal of Heart Failure ( IF 16.9 ) Pub Date : 2024-07-30 , DOI: 10.1002/ejhf.3401
Rafael de la Espriella _{1,

2,

3} , Patricia Palau _{1,

2,

4} , Maurizio Losito ₅ , Giulia Crisci ₅ , Gema Miñana _{1,

2,

3,

4} , Eloy Domínguez _{1,

2} , Vicente Bertomeu-González _{6,

7} , Vicent Bodí _{1,

2,

3,

4} , Juan Sanchis _{1,

2,

3,

4} , Antoni Bayés-Genís _{3,

8,

9} , Kramer J Wahlberg ₁₀ , Markus Meyer ₁₁ , Marco Guazzi ₅ , Julio Núñez _{1,

2,

3,

4}

Affiliation

Cardiology Department, Hospital Clínico Universitario de Valencia, Valencia, Spain.
Instituto de Investigación Sanitaria INCLIVA, Valencia, Spain.
Centro de Investigación Biomédica en Red - Cardiovascular (CIBER-CV), Madrid, Spain.
Department of Medicine, University of Valencia, Valencia, Spain.
Division of Cardiology, University of Milano School of Medicine, San Paolo Hospital, Milan, Italy.
Cardiology Department, Hospital Clínica Benidorm, Benidorm, Spain.
Universidad Miguel Hernández, Alicante, Spain.
Cardiology Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.
Department of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.
Larner College of Medicine, Department of Medicine, University of Vermont, Burlington, VT, USA.
Department of Medicine, Lillehei Heart Institute, University of Minnesota College of Medicine, Minneapolis, MN, USA.

Emerging evidence suggests that smaller left ventricular volumes may identify subjects with lower cardiorespiratory fitness. Whether left ventricular size predicts functional capacity in patients with heart failure with preserved ejection fraction (HFpEF) is unclear. This study aimed to explore the association between indexed left ventricular end-diastolic volume (iLVEDV) and maximal functional capacity, assessed by peak oxygen consumption (peakVO₂), in stable outpatients with HFpEF.

中文翻译：

射血分数保留的心力衰竭患者的左心室容积和最大功能量：大小很重要

新出现的证据表明，较小的左心室容积可以识别心肺健康较低的受试者。左心室大小是否能预测射血分数保留的心力衰竭（HFpEF）患者的功能能力尚不清楚。本研究旨在探讨稳定门诊 HFpEF 患者左心室舒张末期指数容积（iLVEDV）与最大功能能力之间的关联，通过峰值耗氧量（peakVO₂）评估。

更新日期：2024-07-30

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