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Presynaptic and Postsynaptic Mesolimbic Dopamine D3 Receptors Play Distinct Roles in Cocaine Versus Opioid Reward in Mice
Biological Psychiatry ( IF 9.6 ) Pub Date : 2024-06-03 , DOI: 10.1016/j.biopsych.2024.05.020
Zheng-Xiong Xi 1 , Miriam E Bocarsly 2 , Ewa Galaj 1 , Briana Hempel 1 , Catherine Teresi 2 , Marlisa Shaw 2 , Guo-Hua Bi 3 , Chloe Jordan 1 , Emily Linz 3 , Hannah Alton 3 , Gianluigi Tanda 4 , Zachary Freyberg 5 , Veronica A Alvarez 6 , Amy Hauck Newman 1
Affiliation  

Past research has illuminated pivotal roles of dopamine D3 receptors (D3R) in the rewarding effects of cocaine and opioids. However, the cellular and neural circuit mechanisms that underlie these actions remain unclear.

中文翻译:


突触前和突触后中脑边缘多巴胺 D3 受体在可卡因与小鼠阿片类药物奖励中起着不同的作用



过去的研究阐明了多巴胺 D3 受体 (D3R) 在可卡因和阿片类药物的有益作用中的关键作用。然而,支撑这些作用的细胞和神经回路机制仍不清楚。
更新日期:2024-06-03
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