People with short symptom duration of knee osteoarthritis benefit more from exercise therapy than people with longer symptom duration: An individual participant data meta-analysis from the OA trial bank,Osteoarthritis and Cartilage

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People with short symptom duration of knee osteoarthritis benefit more from exercise therapy than people with longer symptom duration: An individual participant data meta-analysis from the OA trial bank
Osteoarthritis and Cartilage ( IF 7.2 ) Pub Date : 2024-07-18 , DOI: 10.1016/j.joca.2024.07.007
M van Middelkoop ₁ , D Schiphof ₁ , M Hattle ₂ , J Simkins ₃ , K L Bennell ₄ , R S Hinman ₄ , K D Allen ₅ , J Knoop ₆ , M E van Baar ₇ , D Bossen ₈ , J Wallis ₉ , M Hurley ₁₀ , M A Holden ₃ , S M A Bierma-Zeinstra ₁

Affiliation

Department of General Practice, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Institute of Applied Health Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
School of Medicine, Primary Care Centre Versus Arthritis, Keele University, Keele, Staffordshire, UK.
Centre for Health, Exercise and Sports Medicine, Department of Physiotherapy, School of Health Sciences, Faculty of Medicine Dentistry & Health Sciences, The University of Melbourne, Melbourne, Australia.
Department of Medicine & Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, USA; Center of Innovation to Accelerate Discovery and Practice Transformation, Department of Veterans Affairs Healthcare System, Durham, NC, USA.
Department of Health Sciences, Faculty of Science and Amsterdam Movement Science, Musculoskeletal Health, Vrije Universiteit, Amsterdam, the Netherlands; Musculoskeletal Rehabilitation research group, HAN University of Applied Sciences, Nijmegen, the Netherlands.
Association of Dutch Burn Centres (ADBC), Burn Centre, Maasstad Hospital, Rotterdam, the Netherlands; Department of Public Health, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Centre of Expertise Urban Vitality, Faculty of Health, Amsterdam University of Applied Sciences, the Netherlands.
School of Public Health and Preventive Medicine, Monash University, Australia; Department of Physiotherapy, Podiatry, Prosthetics and Orthotics, La Trobe University, Australia.
Population Health Research Institute, St George's University of London, UK.

To investigate whether duration of knee symptoms influenced the magnitude of the effect of exercise therapy compared to non-exercise control interventions on pain and physical function in people with knee osteoarthritis (OA).

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