International Classification System for Ocular Complications of Anti-VEGF Agents in Clinical Trials,Ophthalmology

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International Classification System for Ocular Complications of Anti-VEGF Agents in Clinical Trials
Ophthalmology ( IF 13.1 ) Pub Date : 2024-06-13 , DOI: 10.1016/j.ophtha.2024.06.011
Marko M Popovic ₁ , Michael Balas ₁ , SriniVas R Sadda ₂ , David Sarraf ₃ , Ryan Huang ₁ , Sophie J Bakri ₄ , Audina Berrocal ₅ , Andrew Chang ₆ , Chui Ming Gemmy Cheung ₇ , Sunir Garg ₈ , Roxane J Hillier ₉ , Frank G Holz ₁₀ , Mark W Johnson ₁₁ , Peter K Kaiser ₁₂ , Peter J Kertes ₁ , Timothy Y Y Lai ₁₃ , Jason Noble ₁ , Susanna S Park ₁₄ , Yannis M Paulus ₁₁ , Giuseppe Querques ₁₅ , Aleksandra Rachitskaya ₁₂ , Paisan Ruamviboonsuk ₁₆ , Shohista Saidkasimova ₁₇ , Maria Teresa Sandinha ₁₈ , David H Steel ₁₉ , Hiroko Terasaki ₂₀ , Christina Y Weng ₂₁ , Basil K Williams ₂₂ , Lihteh Wu ₂₃ , Rajeev H Muni ₁

Affiliation

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada.
Doheny Eye Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Stein Eye Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota.
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Leonard M. Miller School of Medicine, Miami, Florida.
Sydney Retina Clinic, Sydney Eye Hospital, University of New South Wales, Sydney, Australia.
Department of Ophthalmology, National University of Singapore, Singapore, Republic of Singapore.
Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Wills Eye Hospital, Philadelphia, Pennsylvania.
Newcastle Eye Centre, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom.
Department of Ophthalmology, University of Bonn, Bonn, Germany.
Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan.
Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio.
Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Kowloon, Hong Kong, China.
Department of Ophthalmology & Vision Science, University of California Davis Eye Center, Sacramento, California.
Department of Ophthalmology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
Department of Ophthalmology, College of Medicine, Rangsit University, Rajavithi Hospital, Bangkok, Thailand.
Tennent Institute of Ophthalmology, Glasgow, Scotland, United Kingdom.
Department of Eye and Visual Science, University of Liverpool, Merseyside, United Kingdom.
Sunderland Eye Infirmary, Sunderland, United Kingdom.
Nagoya University Hospital, Nagoya, Japan.
Cullen Eye Institute, Baylor College of Medicine, Houston, Texas.
Cincinnati Eye Institute, Department of Ophthalmology, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Department of Ophthalmology, Asociados de Mácula Vitreo y Retina de Costa Rica, San José, Costa Rica.

Complications associated with intravitreal anti-VEGF therapies are reported inconsistently in the literature, thus limiting an accurate evaluation and comparison of safety between studies. This study aimed to develop a standardized classification system for anti-VEGF ocular complications using the Delphi consensus process.

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