Pesticide ecological safety continues to be a hot issue. The inherent biosafety and physiological functions of vanillin, a widely used natural flavor in food additives, have unlocked numerous applications in the medical field, leading to a plethora of pharmaceutically active derivatives and commercial drugs. Despite its extensive use in pharmaceutical discovery and the food industry, vanillin’s potential in the domain of green pesticide development has only recently come to light. Significantly, its advantages of safety and low price make vanillin ideal for green pesticide research and development (R&D). In this context, this review illuminates the research on vanillin’s transformation into a suite of innovative agrochemicals. By delving into the design, synthesis, action mechanisms, and bio-safety of these vanillin-derived compounds, we uncover novel pathways for sustainable agriculture. Further possible directions for the exploration of this substance are also outlined. We believe that this story about vanillin will serve as a source of inspiration for those seeking to derive innovative ideas from natural substances, particularly in the realm of green pesticide R&D.

中文翻译：

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天然香兰素的农药工程：最新进展和展望


农药生态安全仍是热点问题。香兰素是食品添加剂中广泛使用的天然香料，其固有的生物安全性和生理功能在医疗领域开启了众多应用，导致了大量的药用活性衍生物和商业药物的出现。尽管香兰素在药物发现和食品工业中得到广泛应用，但它在绿色农药开发领域的潜力直到最近才显现出来。值得注意的是，其安全性和低廉的价格优势使香兰素成为绿色农药研发 （R&D） 的理想选择。在此背景下，这篇综述阐明了香兰素转化为一套创新农用化学品的研究。通过深入研究这些香兰素衍生化合物的设计、合成、作用机制和生物安全性，我们发现了可持续农业的新途径。还概述了探索这种物质的更多可能方向。我们相信，这个关于香兰素的故事将为那些寻求从天然物质中获取创新想法的人提供灵感来源，特别是在绿色农药研发领域。