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Environmental implications of dental restorative materials on the zebrafish Danio rerio: Are dental chair drainage systems an emerging environmental threat?
Environmental Toxicology and Pharmacology ( IF 4.2 ) Pub Date : 2024-07-15 , DOI: 10.1016/j.etap.2024.104499 Matea Majstorović 1 , Sanja Babić Brčić 2 , Olga Malev 2 , Matej Par 3 , Igor Živković 4 , Marijan Marciuš 5 , Zrinka Tarle 3 , Rozelindra Čož-Rakovac 2 , Danijela Marović 3
Environmental Toxicology and Pharmacology ( IF 4.2 ) Pub Date : 2024-07-15 , DOI: 10.1016/j.etap.2024.104499 Matea Majstorović 1 , Sanja Babić Brčić 2 , Olga Malev 2 , Matej Par 3 , Igor Živković 4 , Marijan Marciuš 5 , Zrinka Tarle 3 , Rozelindra Čož-Rakovac 2 , Danijela Marović 3
Affiliation
This study aimed to evaluate the environmental impact of dental materials: commercial composite Tetric EvoCeram®, glass ionomer Equia Forte® HT Fil, laboratory-prepared composite, alkasite Cention® Forte, amalgam Amalcap® Plus, and samples from dental chair drainage systems (DCDS). Methacrylate monomers were detected in the eluates of experimental and commercials composites, and alkasite. In DCDS samples solely mercury was found at concentrations of 0.08–1.86 μg/L. The experimental composite (48 h incubation) exhibited the highest toxicity on zebrafish (LC=0.70 g/L), followed by amalgam (LC=8.27 g/L) < Tetric EvoCeram® (LC=10.94 g/L) < Equia Forte® HT Fil (LC=24.84 g/L) < Cention® Forte (LC=32.22 g/L). Exposure of zebrafish to DCDS samples resulted in decreased larval body length and increased occurrences of edema and blood accumulation. The results obtained highlight the need for additional monitoring and further research on the release of unreacted monomers and mercury from dental materials and their environmental impact.
中文翻译:
牙科修复材料对斑马鱼斑马鱼的环境影响:牙科椅排水系统是否是一种新出现的环境威胁?
本研究旨在评估牙科材料对环境的影响:商用复合材料 Tetric EvoCeram®、玻璃离聚物 Equia Forte® HT Fil、实验室制备的复合材料、碱金属 Cention® Forte、汞合金 Amalcap® Plus 以及来自牙科椅排水系统 (DCDS) 的样品)。在实验和商业复合材料以及碱金属的洗出液中检测到甲基丙烯酸酯单体。在 DCDS 样品中仅发现汞浓度为 0.08–1.86 µg/L。实验复合物(孵育 48 小时)对斑马鱼表现出最高毒性 (LC=0.70 g/L),其次是汞合金 (LC=8.27 g/L) < Tetric EvoCeram® (LC=10.94 g/L) < Equia Forte® HT Fil (LC=24.84 g/L) < Cention® Forte (LC=32.22 g/L)。斑马鱼暴露于 DCDS 样本会导致幼虫体长缩短,并增加水肿和血液积聚的发生率。获得的结果强调需要对牙科材料中未反应单体和汞的释放及其对环境的影响进行额外监测和进一步研究。
更新日期:2024-07-15
中文翻译:
牙科修复材料对斑马鱼斑马鱼的环境影响:牙科椅排水系统是否是一种新出现的环境威胁?
本研究旨在评估牙科材料对环境的影响:商用复合材料 Tetric EvoCeram®、玻璃离聚物 Equia Forte® HT Fil、实验室制备的复合材料、碱金属 Cention® Forte、汞合金 Amalcap® Plus 以及来自牙科椅排水系统 (DCDS) 的样品)。在实验和商业复合材料以及碱金属的洗出液中检测到甲基丙烯酸酯单体。在 DCDS 样品中仅发现汞浓度为 0.08–1.86 µg/L。实验复合物(孵育 48 小时)对斑马鱼表现出最高毒性 (LC=0.70 g/L),其次是汞合金 (LC=8.27 g/L) < Tetric EvoCeram® (LC=10.94 g/L) < Equia Forte® HT Fil (LC=24.84 g/L) < Cention® Forte (LC=32.22 g/L)。斑马鱼暴露于 DCDS 样本会导致幼虫体长缩短,并增加水肿和血液积聚的发生率。获得的结果强调需要对牙科材料中未反应单体和汞的释放及其对环境的影响进行额外监测和进一步研究。