The SARS-CoV-2 pandemic has left millions of individuals with a host of post-viral symptoms that can be debilitating and persist indefinitely. To date there are no definitive tests or treatments for the collection of symptoms known as “Long COVID” or Post-acute sequelae of COVID-19 (PASC). Following our initial case report detailing improvement of Long COVID symptoms after sequential bilateral stellate ganglion blockade (SGB), we performed a retrospective chart analysis study on individuals treated with the same protocol over the course of six months (2021−2022) in our clinic. Patients self-reported symptoms on a 10-point scale as part of optional patient follow-up using an online survey. After one month or more following treatment, patients reported striking reductions in Fatigue, Worsening of Symptoms following Mental and Physical Activity, Memory Problems, Problems Concentrating, Sleep Problems, Anxiety, and Depression. Loss of Taste and Loss of Smell in some individuals did not respond to treatment, likely indicating structural damage following infection. This study suggests that neuromodulation may provide relief of Long COVID symptoms for at least a subset of individuals, and provides support for prospective studies of this potential treatment.

中文翻译：

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星状神经节阻滞后长期新冠症状的减轻：一项回顾性图表回顾研究


SARS-CoV-2 大流行使数百万人出现了一系列病毒后症状，这些症状可能使人衰弱并无限期地持续下去。迄今为止，对于被称为“长期新冠病毒”或新冠病毒急性后遗症 (PASC) 的一系列症状，尚无明确的测试或治疗方法。在我们的初始病例报告详细描述了连续双侧星状神经节阻断 (SGB) 后长新冠症状的改善后，我们对在我们诊所六个月（2021−2022 年）内接受相同方案治疗的个体进行了回顾性图表分析研究。作为可选的在线调查患者随访的一部分，患者按照 10 分制自我报告症状。治疗后一个月或更长时间后，患者报告疲劳、精神和体力活动后症状恶化、记忆问题、注意力集中问题、睡眠问题、焦虑和抑郁显着减轻。一些人的味觉丧失和嗅觉丧失对治疗没有反应，这可能表明感染后结构受损。这项研究表明，神经调节可以缓解至少一部分人的长期新冠症状，并为这种潜在治疗方法的前瞻性研究提供支持。