Characteristics of myopic maculopathy in Chinese children and adolescents with high myopia,British Journal of Ophthalmology

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Characteristics of myopic maculopathy in Chinese children and adolescents with high myopia
British Journal of Ophthalmology ( IF 3.7 ) Pub Date : 2024-07-26 , DOI: 10.1136/bjo-2023-324430
Feng Jiang ₁ , Ou Xiao ₁ , Xinxing Guo ₂ , Qiuxia Yin ₁ , Lixia Luo ₁ , Mingguang He _{3,

4,

5} , Zhixi Li ₆

Affiliation

Aims To investigate the characteristics of myopic maculopathy among highly myopic Chinese children and adolescents and explore its associated risk factors. Methods Children and adolescents aged 7–17 years with spherical equivalent (SE) ≤ −6.00 dioptres (D) were recruited. Myopic maculopathy was categorised based on the International Meta-Analysis of Pathological Myopia Classification. The extent of diffuse choroidal atrophy (DCA) was classified using Early Treatment Diabetic Retinopathy Study grid (ETDRS). The area of DCA was categorised into three classes relative to optic disk area (DA): A1 (≤1 DA), A2 (1 to ≤5 DA) and A3 (5 to ≤10 DA). Logistic regression was used to identify risk factors associated with myopic maculopathy. Results Of the 425 participants aged 13.66±2.67 years, the proportions of tessellated fundus and DCA were 11.76% and 12.24%, and no more severe fundus lesions or ‘plus’ lesions. The proportion of DCA was 27.03% in children under 11, significantly higher than the 9.12% observed in those aged 11 and older (p<0.001). The percentages of DCA involving the outer, middle and central circles of the ETDRS grid were 42.31%, 55.77% and 1.92%. Myopic maculopathy was significantly associated with younger age (p<0.001), longer axial length (AL; p<0.001) and larger β-zone peripapillary atrophy (β-PPA; p=0.012). Conclusion In highly myopic children and adolescents, myopic maculopathy predominantly manifested as DCA (12.24%), with no cases of worse myopic maculopathy or ‘plus’ lesions. Younger age, longer AL and larger β-PPA were risk factors for myopic maculopathy. No data are available.

更新日期：2024-07-27

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