The objective of this research was to determine the effects of mid-gestational maternal inflammation on performance, carcass characteristics, and meat quality of offspring. Pregnant gilts were administered either lipopolysaccharide (LPS; n=7) or saline (CON, n=7) from d 70-84 of gestation. Gilts assigned to the LPS treatment were administered an intravenous injection of reconstituted LPS every other day with a beginning does of 10 μg LPS/kg BW and subsequent doses increasing by 12%, while CON gilts received intravenous injections of comparable volumes of saline. Gilts farrowed naturally, and at d 66 of age a total of 59 pigs, both barrows and gilts began a 3-phase feeding regimen designed to meet or exceed nutrient requirements for growing-finishing pigs. Pigs were weighed on d 0, 35, 70, and 105 of the finishing trial to determine ADG, ADFI, and G:F. On d 106, pigs were slaughtered under supervision of the United States department of Agriculture Food Safety Inspection Service (USDA-FSIS). Ending live weight (ELW), hot carcass weight (HCW), and dressing percentage were determined. Left side of carcasses were weighed and fabricated to determine carcass cutting yields. The semitendinosus was collected for histological samples. Fresh belly characteristics and loin quality were measured. Two chops were collected for Warner-Bratzler shear force (WBSF) and proximate analysis. No differences (P ≥ 0.13) between LPS and CON pigs were observed for growth performance in phases 1, 2, 3, or overall (d 0-105) performance with the exception of overall G:F reduced in CON pigs compared with LPS pigs (P = 0.03). There was a tendency for carcass yield to be reduced (P = 0.06; 0.82% units) in LPS pigs compared with CON pigs. Additionally, longissimus muscle area (LMA) tended to be reduced (P = 0.10) 2.27 cm2 in LPS compared with CON pigs. Loin chop quality traits including instrumental color, subjective color, marbling, firmness, pH, and drip loss were not different (P ≥ 0.09) between LPS and CON pigs. Fresh belly characteristics were not different (P ≥ 0.22) between LPS and CON pigs. There were no differences in primal and subprimal weights, except for LPS pigs tended to have a reduction (P ≥ 0.07) in tenderloin and Canadian back weights compared with CON pigs. Furthermore, LPS pigs had no differences (P ≥ 0.25) in muscle fiber composition or size, however LPS pigs tended (P = 0.10) to have a 13% reduction in estimated muscle fibers number compared with CON pigs. In summary, mid gestational inflammation did not result in reduced meat quality, growth performance, or carcass yields of offspring.

中文翻译：

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母猪炎症对子代猪生长性能、胴体特性及肉品质的影响


本研究的目的是确定妊娠中期母体炎症对后代生产性能、胴体特性和肉质的影响。从妊娠第 70-84 天开始，对怀孕的后备母猪施用脂多糖（LPS；n=7）或盐水（CON，n=7）。接受 LPS 治疗的后备母猪每隔一天静脉注射一次重组 LPS，起始剂量为 10 μg LPS/kg BW，随后剂量增加 12%，而 CON 后备母猪接受静脉注射相当体积的盐水。后备母猪自然分娩，在第 66 天时，共有 59 头猪，母猪和后备母猪开始了 3 阶段饲喂方案，旨在满足或超过生长育肥猪的营养需求。在育肥试验的第 0、35、70 和 105 天对猪进行称重，以确定 ADG、ADFI 和 G:F。 106天，生猪在美国农业部食品安全检验局（USDA-FSIS）的监督下被屠宰。确定最终活重（ELW）、热胴体重量（HCW）和屠宰率。对屠体左侧进行称重和制作以确定屠体切割产量。收集半腱肌作为组织学样本。测量了新鲜的腹部特征和腰肉质量。收集两个切片用于 Warner-Bratzler 剪切力 (WBSF) 和近似分析。 LPS 和 CON 猪之间在第 1、2、3 阶段的生长性能或总体 (d 0-105) 性能方面没有观察到差异 (P ≥ 0.13)，但与 LPS 猪相比，CON 猪的总体 G:F 有所降低。 （P = 0.03）。与 CON 猪相比，LPS 猪的胴体产量有降低的趋势（P = 0.06；0.82% 单位）。 此外，与 CON 猪相比，LPS 猪的最长肌面积 (LMA) 倾向于减少 (P = 0.10) 2.27 cm2。 LPS 猪和 CON 猪之间的腰排质量性状（包括仪器颜色、主观颜色、大理石花纹、硬度、pH 值和滴水损失）没有差异 (P ≥ 0.09)。 LPS 猪和 CON 猪之间的新鲜腹部特征没有差异 (P ≥ 0.22)。原始体重和次原始体重没有差异，但与 CON 猪相比，LPS 猪的里脊肉和加拿大背肉重量倾向于减少（P ≥ 0.07）。此外，LPS 猪的肌纤维组成或大小没有差异 (P ≥ 0.25)，但与 CON 猪相比，LPS 猪的估计肌纤维数量倾向于 (P = 0.10) 减少 13%。总之，妊娠中期炎症不会导致后代肉质、生长性能或胴体产量下降。