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Cell-Free DNA Analysis for the Determination of Fetal Red Blood Cell Antigen Genotype in Individuals With Alloimmunized Pregnancies.
Obstetrics and Gynecology ( IF 5.7 ) Pub Date : 2024-07-25 , DOI: 10.1097/aog.0000000000005692
Shannon Rego 1 , Olaide Ashimi Balogun , Kirsten Emanuel , Rachael Overcash , Juan M Gonzalez , Gregory A Denomme , Jennifer Hoskovec , Haley King , Ashley Wilson , Julia Wynn , Kenneth J Moise
Affiliation  

To evaluate the accuracy of next-generation sequencing-based quantitative cell-free DNA analysis for fetal antigen genotyping in individuals with alloimmunized pregnancies undergoing clinical testing in practices across the United States as early as 10 weeks of gestation, with the objective of identifying individuals with pregnancies at risk for hemolytic disease of the fetus and newborn and guiding management.

中文翻译:


用于测定同种异体免疫妊娠个体胎儿红细胞抗原基因型的游离 DNA 分析。



评估基于下一代测序的定量游离 DNA 分析对胎儿抗原基因分型的准确性,这些个体最早在妊娠 10 周时在美国各地的实践中接受临床检测,目的是识别有胎儿和新生儿溶血病风险的孕妇个体并指导管理。
更新日期:2024-07-25
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