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Assessing the Relevance of Non-molecular Prognostic Systems for Myelodysplastic Syndrome in the Era of Next-Generation Sequencing.
Annals of Laboratory Medicine ( IF 4.0 ) Pub Date : 2024-07-26 , DOI: 10.3343/alm.2024.0089
Marco Lincango 1 , Verónica Andreoli 2 , Hernán García Rivello 3 , Andrea Bender 4 , Ana I Catalán 5 , Marilina Rahhal 6 , Rocío Delamer 7 , Mariana Asinari 2 , Adrián Mosquera Orgueira 8 , María Belén Castro 2 , María José Mela Osorio 7 , Alicia Navickas 6 , Sofia Grille 5 , Evangelina Agriello 4 , Jorge Arbelbide 3 , Ana Lisa Basquiera 2 , Carolina B Belli 1
Affiliation  

The Molecular International Prognostic Scoring System (IPSS-M) has improved the prediction of clinical outcomes for myelodysplastic syndromes (MDS). The Artificial Intelligence Prognostic Scoring System for MDS (AIPSS-MDS), based on classical clinical parameters, has outperformed the IPSS, revised version (IPSS-R). For the first time, we validated the IPSS-M and other molecular prognostic models and compared them with the established IPSS-R and AIPSS-MDS models using data from South American patients.

中文翻译:


评估下一代测序时代骨髓增生异常综合征非分子预后系统的相关性。



国际分子预后评分系统 (IPSS-M) 改进了骨髓增生异常综合征 (MDS) 临床结果的预测。基于经典临床参数的 MDS 人工智能预后评分系统 (AIPSS-MDS) 的性能优于 IPSS 修订版 (IPSS-R)。我们首次验证了 IPSS-M 和其他分子预后模型,并将其与使用南美患者数据建立的 IPSS-R 和 AIPSS-MDS 模型进行了比较。
更新日期:2024-07-26
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