A new study combines massively parallel assays, transcriptomics and biophysical modeling to provide a framework for analyzing the effects of compounds that modulate pre-mRNA splicing. The results lend important insights into the mechanisms of drug action and facilitate the design of splicing therapies.

中文翻译：

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剪接修饰药物机制


一项新研究结合了大规模并行测定、转录组学和生物物理模型，为分析调节前 mRNA 剪接的化合物的作用提供了一个框架。这些结果为了解药物作用机制提供了重要见解，并有助于剪接疗法的设计。