The degree of ease of use and the readily observable signals associated with the detection process are critical factors in determining the success of a detection strategy. Keeping this viewpoint in mind, we have reported the detection of phosgene, achieved by modulating the photophysical characteristics of a molecular probe, Xanth-NH2. The probe is non-emissive in nature, but the presence of phosgene facilitates the probe's radiative decay, which enables phosgene detection via fluorescence turn-on change. The fluorescence changes vary linearly with phosgene concentration, contributing to a nanomolar level detection limit for phosgene. Additionally, under the controlled set of conditions, the half-time for the reaction of Xanth-NH2 with phosgene is 68 seconds. To demonstrate the potential application of Xanth-NH2, probe-loaded paper strips or silica gel were developed as an economic tool for the vapor or solution phase detection of phosgene. Furthermore, phosgene detection has been accomplished with a portable UV light source and a smartphone in order to track minute changes during the detection event.

中文翻译：

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通过分析物触发异氰酸酯形成对光气进行基于呫吨的荧光开启检测


与检测过程相关的易用程度和易于观察的信号是决定检测策略成功的关键因素。考虑到这一观点，我们报道了通过调节分子探针 Xanth-NH2 的光物理特性来实现光气的检测。该探针本质上是不发射的，但光气的存在促进了探针的辐射衰变，从而能够通过荧光开启变化来检测光气。荧光变化随光气浓度线性变化，从而达到纳摩尔水平的光气检测限。此外，在受控条件下，Xanth-NH2 与光气的反应半衰期为 68 秒。为了证明 Xanth-NH2 的潜在应用，开发了负载探针的纸条或硅胶作为光气气相或液相检测的经济工具。此外，光气检测是通过便携式紫外光源和智能手机完成的，以便跟踪检测事件期间的微小变化。